Results 181 to 190 of about 454,030 (362)

Calpain‐2‐Mediated Endothelial Focal Adhesion Disruption in Thoracic Aortic Dissection

open access: yesAdvanced Science, EarlyView.
The elevated expression of Capn2 in endothelial cells activates focal adhesion signaling by cleaving Talin1 and assembling Itgav, which compromises the integrity of the endothelial barrier and induces vascular inflammation. Inhibition of calpain through both pharmacological and transgenic approaches has effectively suppressed the onset and progression ...
Xiaomei Teng   +10 more
wiley   +1 more source

Sexuality in patients with human immunodeficiency virus at Embhuleni Hospital in Mpumalanga province [PDF]

open access: bronze, 2013
Elma De Vries   +2 more
openalex   +1 more source

Sexuality among People with Physical Disability [PDF]

open access: yes, 2012
Physical disability is termed as disturbance or defect which impede or eliminate human body’s ability by disturbing human structure and shape. Physical disability may occur due to neonatal, natal or postnatal causes.
Behice Han Almis   +2 more
core  

A Dual‐Modal Wearable Pulse Detection System Integrated with Deep Learning for High‐Accuracy and Low‐Power Sleep Apnea Monitoring

open access: yesAdvanced Science, EarlyView.
A dual‐modal wearable pulse detection system is developed for sleep apnea monitoring by integrating a self‐powered PENG and PPG sensor with a biomimetic fingertip structure. Through a two‐stage detection strategy, continuous PPW monitoring and on‐demand PPG detection achieve high‐accuracy sleep apnea recognition while maintaining low power consumption.
Jia Wang   +10 more
wiley   +1 more source

Colorectal Cancer Cells–Derived Exosomal PIK3CA Mutation DNA Promotes Tumor Metastasis by Activating Fibroblast and Affecting Tumor Metastatic Microenvironment

open access: yesAdvanced Science, EarlyView.
PIK3CAH1047R DNA in colorectal cancer (CRC) cell‐derived exosomes can be delivered into recipient fibroblasts, where it is transcribed and translated, leading to the activation of fibroblasts into cancer‐associated fibroblasts, which secrete elevated levels of IL6. The simultaneous detection and targeting of PIK3CAH1047R mutation and IL6 may serve as a
Rui Wang   +6 more
wiley   +1 more source

The Social Construction of Sexuality in Primary School Classrooms [PDF]

open access: yes, 2014
Through qualitative interviews with primary school teachers, this research sought to uncover how heterosexual privilege is maintained in talk about sexuality.
Spengen, Anna
core   +1 more source

Genetic Regulation of Alternative Polyadenylation Provides Novel Insights into Molecular Mechanisms Underlying Non‐small Cell Lung Cancer

open access: yesAdvanced Science, EarlyView.
Compared with the non‐risk G allele of rs9606, the risk T allele of rs9606 decreases the binding affinity of NUDT21 for LYRM4, triggering 3'UTR shortening that stabilizes LYRM4 mRNA and elevates its expression. Increased LYRM4 expression promoted malignant phenotypes of non‐small cell lung cancer (NSCLC) cells through modulating ferroptosis, supporting
Meng Jin   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy