Results 191 to 200 of about 454,030 (362)
Development and validation of the scale of knowledge, comfort and attitudes of physiotherapy students towards human sexuality (SKCAPS) [PDF]
, 2015 Priscilla Geraldine Wittkopf +2 more
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Biblica et Patristica Thoruniensia, 2019 The starting point in the Jewish religion for all reflections on the subject of the body, and hence also on sexuality, is the biblical image of man as "imago Dei". Thus in Judaism there are no forms of duality in which there would be an aporia between the flesh and the spiritual.
openaire +3 more sources
Advanced Science, EarlyView.This study demonstrates that mutant FAT1 promotes ASCL2‐driven, CPT1A‐dependent fatty acid oxidation, leading to resistance to CPI‐613‐mediated TCA cycle inhibition in head and neck cancer. In vivo gene depletion of mutant FAT1 with LNP‐sgFAT1 suppresses tumor growth and restores CPI‐613 sensitivity, revealing a targetable metabolic bypass with ...
Fanghui Chen +11 more
wiley +1 more source
Advanced Science, EarlyView.Doxorubicin‐induced cardiomyopathy involves mitochondrial energy metabolism dysfunction, exacerbated by cardiomyocyte‐specific Slc25a49 deficiency via oxidative phosphorylation (OXPHOS) suppression and glycolysis activation. The Slc25a49–glucose‐6‐phosphate (G6P)–activator protein‐1 (AP‐1) axis drives myocardial injury by upregulating Sln, disrupting ...
Sitong Wan +16 more
wiley +1 more source
Advanced Science, EarlyView.This study presents an explainable multimodal AI model, MAIGGT (Multimodal Artificial Intelligence Germline Genetic Testing), that combines whole‐slide histopathology with clinical data for accurate germline BRCA1/2 mutation prescreening. By integrating digital pathology and EHR phenotypes, MAIGCT enables cost‐effective, scalable hereditary breast ...
Zijian Yang +23 more
wiley +1 more source
Julius von Sachs’ forgotten 1897-article: sexuality and gender in plants vs. humans [PDF]
, 2018 U. Kutschera, Karl J. Niklas
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LIMK1 as a Novel Kinase of β‐Catenin Promotes Esophageal Cancer Metastasis by Cooperating With CDK5
Advanced Science, EarlyView.Li et al. innovatively map the kinase‐substrate network in esophageal cancer metastasis. Their study demonstrates that LIM domain kinase 1 (LIMK1) and Cyclin‐dependent kinase 5 (CDK5) synergistically increase the phosphorylation of β‐catenin, thereby activating the Wnt/β‐catenin signaling pathway to promote esophageal cancer metastasis.
Shu‐Jun Li +27 more
wiley +1 more source