Results 191 to 200 of about 402,590 (343)

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source

Sexuality in the field of occupational therapy: A scoping review. [PDF]

Aust Occup Ther J
Auger LP, Vinette B, Potvin L, Nelson-Drolet S, Thomas A.   +4 more
europepmc   +1 more source

Nursing students’ perception of training on human sexuality

, 2017
Maria das Neves Figueiroa, Maria Lúcia Neto de Menezes, Estela Maria Leite Meirelles Monteiro, Ângela Andrade, Débora Priscila Ferreira Fraga, Monique Vieira de Oliveira   +5 more
openalex   +2 more sources

Homosexuality and the Mental Health Professions: The Impact of Bias Formulated by the Committee on Human Sexuality. Hillsdale, NJ: Analytic Press. 2000. 132 pp. £22.50 (hb). ISBN 0 881 63318 6 [PDF]

, 2001
Sidney Crown, Alan Lee, Michael King
openalex   +1 more source

The Tumor‐to‐Endothelial Transfer of FTO Promotes Vascular Remodeling and Metastasis in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
Integrated omics analysis of matched primary and liver metastatic NPC tumors reveals a unique NOTCH1+ CSC subpopulation exhibiting enhanced stemness properties and tumorigenic capacity. With in vitro and in vivo assays, exosomal transfer of tumor‐derived FTO from NOTCH1+ cells to the endothelium promotes vascular permeability and metastatic potential ...
Chun Wu, Xuefei Liu, Liwen Gu, Jingru Lian, Yuting Wang, Yixin Cheng, Lianhui Duan, Guanyin Huang, Siqi Chen, Boxi Zhao, Sailan Liu, Yufan Yang, Shuqian Zheng, Zijian Lu, Wanping Guo, Jianyang Hu, Wenjing Wang, Zhixiang Zuo, Haiqiang Mai, LinQuan Tang, Songfa Zhang, Feiqiu Wen, Xin Hong, Ling Guo   +23 more
wiley   +1 more source

Sex, Gender and Sexuality in Oral Health Research: Setting the Scene. [PDF]

Adv Dent Res
Jamieson L, Soares G, Randall C.
europepmc   +1 more source

Human Sexuality and the Celibate Members of the Family of God [PDF]

, 1968
Van Greunsvan, N.J.J.
core   +1 more source

5‐Hydroxymethylcytosine Dynamics Reveals Coordinated Reprogramming of Parental Genomes and X Chromosome Dosage Balance in Mouse SCNT Embryos

Advanced Science, EarlyView.
Genome‐wide, high‐resolution profiling of hydroxymethylation in mouse SCNT embryos reveals a transient, allele‐symmetric 5hmC reprogramming pattern distinct from natural embryos, with X‐chromosomes and imprinting control regions resistant to proper remodeling.
Zeming Xiang, Rui Yan, Jing Guo, Mengyao Wang, Xin Cheng, Fan Zhang, Tianzi Guo, Xin Long, Fan Guo, Dan Liang   +9 more
wiley   +1 more source

Correction to: Brief intervention to prevent HIV, STI and unintended pregnancies: preliminary results of a feasibility study from the perspective of healthcare providers in Peru

BMC Health Services Research, 2021
Jean Pierre Jiron, Clara Sandoval, Juan Carlos Enciso, Ana Sofía De Vasconcelos, Karel Blondeel, Nataliia Bakunina, Galina Lesco, Igor Toskin, Rob Stephenson, Carlos F. Caceres   +9 more
doaj   +1 more source

NAD⁺ Reduction in Glutamatergic Neurons Induces Lipid Catabolism and Neuroinflammation in the Brain via SARM1

Advanced Science, EarlyView.
NAD⁺ homeostasis maintains neuronal integrity through opposing actions of NMNAT2 and SARM1. Loss of NMNAT2 in glutamatergic neurons reprograms cortical metabolism from glucose to lipid catabolism, depletes lipid stores, and triggers inflammation and neurodegeneration.
Zhen‐Xian Niou, Sen Yang, Andrea Enriquez, Nino A. Espinas, Anoosha Sri, Caliel D. Hines, Jason M. Tennessen, Chia‐Shan Wu, Jui‐Yen Huang, Hui‐Chen Lu   +9 more
wiley   +1 more source