Results 221 to 230 of about 8,819,593 (390)

How do 15–16 year old students use scientific knowledge to justify their reasoning about human sexuality and relationships?

, 2016
Mats Lindahl, Mattias Lundin
openalex   +1 more source

Vitiligo Signature‐Based Drug Screening Identifies Fulvestrant as a Novel Immunotherapy Combination Strategy

Advanced Science, EarlyView.
A vitiligo‐derived gene signature predicts response to immune checkpoint blockade across multiple cancer cohorts, providing a framework for patient stratification. Building on this, Fulvestrant—a clinically approved estrogen receptor degrader—further enhances antitumor immunity by reprogramming tumor‐associated macrophages and promoting CD8⁺ T cell ...
Jie Zhu, Liting Huang, Suzhen Bi, WeiKaixin Kong, Wanting Feng, Yingjia Li, Zhengwei Xie, Peipei Shan, Sujie Zhu   +8 more
wiley   +1 more source

Snord15b Maintains Stemness of Intestinal Stem Cells via Enhancement of Alternative Splicing of Btrc Short Isoform for Suppression of β‐Catenin Ubiquitination

Advanced Science, EarlyView.
In intestinal stem cells (ISCs), Snord15b associates with Ilf2 to recruit splicing factors for alternative splicing of Btrc mRNA, leading to the generation of short Btrc. This short Btrc fails to form a functional E3 ubiquitin ligase complex for β‐catenin ubiquitination and degradation.
Yuwei Xu, Peikang Zhang, Zhen Xiong, Yufei Lan, Hui Guo, Runyuan Wu, Cunzhen Li, Hongzhe Fan, Ying Du, Xiaoxiao Zhu, Dongdong Fan, Zhonglong Wang, Yong Tian, Zusen Fan   +13 more
wiley   +1 more source

Human Sexuality and the Celibate Members of the Family of God [PDF]

, 1968
Van Greunsvan, N.J.J.
core   +1 more source

'Our rights, Our lives, Our future': evaluation of a 5-year multi-country programme to enhance sexuality education in sub-Saharan Africa. [PDF]

Reprod Health
Kok M, Kabelka H, Kakal T, Zulu JM, Moukam L, Machawira P, Hamandawana Y, Le Mat M.   +7 more
europepmc   +1 more source

Arginine Metabolic Disruption Impairs Hair Regeneration via ROS‐Mediated Inactivation of mTOR Signaling in Androgenetic Alopecia

Advanced Science, EarlyView.
Arginine deficiency accelerates androgenetic alopecia. Serum metabolome shows reduced circulating arginine, while local metabolic disruption depletes follicular reserves, triggering reactive oxygen species (ROS) accumulation and mTOR suppression that induce hair miniaturization.
Shixin Duan, Guo Li, Yanji Chu, Junbo Zhang, Li Yang, Yujin Zhang, Fangfen Liu, Jiayun Li, Mengting Chen, Ben Wang, Zhixiang Zhao, Wei Shi, Yiya Zhang, Guangtong Deng, Xinwei Kuang, Hongfu Xie, Yufan Cheng, Zhili Deng, Ji Li, Yan Tang   +19 more
wiley   +1 more source

Individual differences play an important role in explaining human sexuality and its impact Upon Ageing Successfully

, 2018
Matt Broadway-Horner
openalex   +1 more source

Norepinephrine Induces Sertoli Cell Ferroptosis via Receptors Desensitization Causing Stress‐Related Male Reproductive Dysfunction

Advanced Science, EarlyView.
Psychological stress activates the sympathetic–adrenal axis, elevating norepinephrine (NE) and suppressing reproductive hormones, thereby impairing male reproduction. Excess NE overactivates and desensitizes β‐adrenergic receptors (β‐ARs), triggering Sertoli cell ferroptosis and disrupting spermatogenesis.
Lingyu Zhang, Shanfeng Gao, Xiaofan Xiong, Xin Liu, Rufeng Li, Xia Wang, Lin Han, Xuan Xiao, Xiaofei Wang, Wen Li, Yongxia Chang, Yuefeng Du, Juan Yang   +12 more
wiley   +1 more source

Correction to: Brief intervention to prevent HIV, STI and unintended pregnancies: preliminary results of a feasibility study from the perspective of healthcare providers in Peru

BMC Health Services Research, 2021
Jean Pierre Jiron, Clara Sandoval, Juan Carlos Enciso, Ana Sofía De Vasconcelos, Karel Blondeel, Nataliia Bakunina, Galina Lesco, Igor Toskin, Rob Stephenson, Carlos F. Caceres   +9 more
doaj   +1 more source

Investigation of the Correlation Between Aspects of Sexuality, Self-Esteem, Anxiety, and Depression in Health Professionals in Central Greece. [PDF]

Cureus
Gkouletsa K, Mitrakas L, Fradelos EC, Bakalis VI, Zetta S, Saridi M.   +5 more
europepmc   +1 more source