Results 271 to 280 of about 402,590 (343)

Endothelial Cell‐Specific Molecule‐1 (ESM1): An Endogenous Anticoagulant and Protective Factor in Venous Thrombosis

Advanced Science, EarlyView.
This study identifies ESM1 as an endogenous anticoagulant that modulates venous thrombosis. It shows that ESM1 deficiency triggers vascular occlusion in zebrafish and mice, whereas its restoration or overexpression prolongs clot‐formation time. Mechanistic analyses reveal that ESM1 activates HCII through its dermatan‐sulfate chain, uncovering a ...
Changsheng Chen, Xiaojuan Ge, Dongxu Fu, Haijun Mei, Feng Lv, Chao Yang, Jiahao Lu, Xiaozhong Shen, Bowen Li, Xiaoning Wang, Dong Liu   +10 more
wiley   +1 more source

Label‐Free Leukocyte Biophysical Profiling Using Impedance‐Deformability Cytometry for Rapid Cardiovascular Risk Stratification

Advanced Science, EarlyView.
This study presents an impedance‐based single‐cell profiling platform that quantifies the electrical and mechanical properties of neutrophils across in vitro, in vivo, and clinical samples. The approach reveals distinct biophysical alterations associated with type 2 diabetes (T2DM) and cardiovascular complications, suggesting its potential utility for ...
Linwei He, Hui Min Tay, Feng Chen, Hong Sheng Cheng, Liang De Wang, Qiqi Nam, Arunachalam Thannirmalai, Lingyan Gong, Aram J. Chung, Nguan Soon Tan, King Ho Holden Li, Rinkoo Dalan, Siu Ling Wong, Han Wei Hou   +13 more
wiley   +1 more source

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

Lexicographic qualitative approach of nurse's perspectives on men's access to sexual health care in Portugal. [PDF]

Sci Rep
Tereso A, Curado A, Brantes A, Fernandes J, Santos R, Antunes L.   +5 more
europepmc   +1 more source

TP53BP2 Promotes Placental Autophagy and Preeclampsia via G9a and DNMT1 Cooperatively Modulating E2F1

Advanced Science, EarlyView.
G9a, and DNA Methyltransferase1 (DNMT1) cooperatively modulates E2F1 on the promoter of tumor suppressor p53‐binding protein 2 (TP53BP2) increased autophagy in preeclampsia. TP53BP2 promotes autophagy in trophoblasts through DNA methylation and H3K9me2‐mediated transcriptional regulation.
Nan Jiang, Shaoju Jin, Shaoying Wen, Wen Zeng, Chen Wang, Jingyu Wang, Qingyun Song, Guizhong Li, Pengzhi Yin, Yuhui Liao, Yuee Chai, Huiping Zhang, Shengchao Ma   +12 more
wiley   +1 more source

An Assessment of the Understanding of Human Sexuality Concepts Among Undergraduates at South Dakota State University

, 1978
Les C. Odegaard
openalex   +1 more source

Tackling difficult topics: Cultural differences and human sexuality in family practice training

, 1998
Élaine Hémond
openalex  

The Impact of Anosmia on Intimacy: A Linear Mixed-Effects Model Analysis of Sexual Wellbeing Following COVID-19. [PDF]

Int J Environ Res Public Health
Miclet A, Mollaioli D, Lauriola M, Ciocca G, Sansone A, Jannini EA, Limoncin E.   +6 more
europepmc   +1 more source

Gender Justice In The Americas: A Transnational Dialogue On Sexuality, Violence, Reproduction, And Human Rights

, 2011
Alma Luz Beltrán y Puga, Caroline Bettinger-López, Jorge Contesse, Paola Garcia-Rey, Diana Hortsch, Risa E. Kaufman, Nicole Tuszynski   +6 more
openalex   +1 more source

The Double Historicity of Sex and Gender. [PDF]

Arch Sex Behav
Thinius A.
europepmc   +1 more source