KIF5A p.Pro986Leu Risk Variant and Accelerated Progression of Amyotrophic Lateral Sclerosis
ABSTRACT This study explored the impact of KIF5A rs113247976 (p.Pro986Leu), a risk allele for amyotrophic lateral sclerosis (ALS), on phenotypic variability in two Italian ALS cohorts (discovery, n = 865; replication, n = 1174). The minor allele (T) frequency was 0.015.
Arianna Manini+24 more
wiley +1 more source
本研究以身分認同的角度切入,探究七位大學女性教師,做為一個女性主義教師是如何的存在與作為?「女性主義教師」是在怎樣的過程中,於她們心中形成意義與實踐方向?她們如何思考女性主義教學行動?本研究發現,女性主義是受訪教師女性意識與覺知生命經驗中性別議題之最初啟蒙,在擔任教職後,女性主義教育學即成為她們教學實踐之主要信仰。然而,成為女性主義教師的實踐歷程中,現實的教學者與改革者之雙重主體位置,加上校園組織結構與權力的限制,使得她們的女性主義教學行動受挫,甚而動搖這樣的身分認同 ...
楊幸真 Hsing-Chen Yang
doaj
Same-sex practices are commonly medicalised in various global spaces. Some societies view same-sex practices as some form of disease that needs to be cured. In Africa, the influence of Christianity has prompted many communities to conclude that there are
Themba Shingange+1 more
doaj +1 more source
Amitriptyline and Sexual Function: A Systematic Review Updated for Sexual Health Practice
Amitriptyline is an old drug but is still prevalently used as the first-line treatment for a variety of common diseases. Surprisingly, knowledge of sexual risks with amitriptyline comes from only one clinical trial and several case reports from three ...
Louis Wei-Hsi Chen MD, MSc, LLM+7 more
doaj +1 more source
CNS Mitochondria‐Derived Vesicle in Blood: Potential Biomarkers for Brain Mitochondria Dysfunction
ABSTRACT Objective Mitochondrial dysfunction is a hallmark of neurodegenerative diseases like Alzheimer's (AD) and Parkinson's (PD). Our goal was to develop practical, noninvasive methods to assess mitochondrial status through the detection of mitochondria‐derived vesicles (MDVs).
Qi Liu+12 more
wiley +1 more source
Addressing unique challenges and crafting inclusive policies for Queer living with disabilities
Background: This article addresses the intersectional challenges faced by Queer people living with disabilities (QPwD). Objectives: The article aims to highlight the nature and extent of their struggles while proposing inclusive policies for societal ...
Ikekhwa A. Ikhile+2 more
doaj +1 more source
Experiences of patients with attention-deficit/hyperactivity disorder and premature ejaculation: a phenomenological study [PDF]
Premature ejaculation is listed in the Diagnostic and Statistical Manual of Mental Disorders and is one of the most common ejaculation disorders in the male population.
Jessica García-González+6 more
doaj +1 more source
QTBIPOC PD: Exploring the Intersections of Race, Gender, and Sexual Orientation in Participatory Design [PDF]
As Human-Computer Interaction (HCI) research aims to be inclusive and representative of many marginalized identities, there is still a lack of available literature and research on intersectional considerations of race, gender, and sexual orientation, especially when it comes to participatory design.
arxiv
A PANoptosis‐Based Signature for Survival and Immune Predication in Glioblastoma Multiforme
ABSTRACT Objective PANoptosis is a concept of total cell death characterized by pyroptosis, apoptosis, and necroptosis. We aimed to explore the clinical significance of PANoptosis‐related genes (PARGs) in glioblastoma multiforme (GBM). Methods Expression profiles of GBM were downloaded from the XENA database as a training dataset to construct a ...
Jun Yang+4 more
wiley +1 more source
Misusing Freud: Psychoanalysis and the Rise of Homosexual Conversion Therapy
Current ideas of conversion therapy often focus on extremist religious groups that wish to cleanse the world of what they view as an immoral abomination, homosexuality. However, conversion therapy started out as mostly scientific curiosity. Sigmund Freud’
Barrett, Jonathan
core