Results 71 to 80 of about 8,819,593 (390)

The Lightness of the Sexual Being: A Short Reflection on Hans Christian Andersen’s “The Little Mermaid”

open access: yesSocieties, 2018
Hans Christian Andersen’s tale, “The Little Mermaid,” has been adored by both children and parents for decades. The tale shows an astonishingly different quality to Andersen’s early genre of fairy tales, which allows the reader to sense his keenness on ...
Seungyeon Lee
doaj   +1 more source

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf   +10 more
wiley   +1 more source

Produção científica da área da saúde sobre a sexualidade humana Health scientific production on human sexuality

open access: yes, 2014
Background: Human sexuality is often treated in a limited way during academic formation, harming knowledge building. The analysis of scientific pro-duction facilitates the understanding of the identity of the research field and points the way forward ...
G. Silveira   +2 more
semanticscholar   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Brief intervention to prevent HIV, STI and unintended pregnancies: preliminary results of a feasibility study from the perspective of healthcare providers in Peru

open access: yesBMC Health Services Research, 2021
Background Brief interventions have proven to be valuable instruments for the treatment and care of clients with diverse health needs, due to their potential to impact both the individual and the population.
Jean Pierre Jiron   +9 more
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

open access: yesFEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian   +6 more
wiley   +1 more source

成為女性主義教師:身分認同與實踐經驗的意義探問 Becoming a Feminist Teacher: The Sensemaking of Feminist Teachers Identities and Practicing

open access: yes臺灣教育社會學研究, 2009
本研究以身分認同的角度切入,探究七位大學女性教師,做為一個女性主義教師是如何的存在與作為?「女性主義教師」是在怎樣的過程中,於她們心中形成意義與實踐方向?她們如何思考女性主義教學行動?本研究發現,女性主義是受訪教師女性意識與覺知生命經驗中性別議題之最初啟蒙,在擔任教職後,女性主義教育學即成為她們教學實踐之主要信仰。然而,成為女性主義教師的實踐歷程中,現實的教學者與改革者之雙重主體位置,加上校園組織結構與權力的限制,使得她們的女性主義教學行動受挫,甚而動搖這樣的身分認同 ...
楊幸真 Hsing-Chen Yang
doaj  

A decolonial analysis of religious medicalisation of same-sex practices in South African Pentecostalism

open access: yesHTS Teologiese Studies/Theological Studies
Same-sex practices are commonly medicalised in various global spaces. Some societies view same-sex practices as some form of disease that needs to be cured. In Africa, the influence of Christianity has prompted many communities to conclude that there are
Themba Shingange   +1 more
doaj   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

open access: yesFEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić   +3 more
wiley   +1 more source

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