Results 211 to 220 of about 976,647 (347)

Fluorinated Carnitine Derivatives as Tools to Visualise Carnitine Transport and Metabolism

Advanced Science, EarlyView.
Fluorinated carnitines, fluoromethyl carnitine (FMC) and [18F]fluoromethyl carnitine ([18F]FMC), are synthesised and established as powerful probes to interrogate carnitine biology. The multimodal detection facilitated by fluorine labelling, including 19F NMR, mass spectrometry, and positron emission tomography imaging, allowed for visualisation of ...
Richard S. Edwards, Ella‐May Hards, Sofia N. dos Santos, Hannah E. Greenwood, Madeleine E. George, Andrea Emanuelli, Muhammet Tanc, Thomas R. Eykyn, Timothy H. Witney   +8 more
wiley   +1 more source

X-Linked Hypophosphatemia: Role of Fibroblast Growth Factor 23 on Human Skeletal Muscle-Derived Cells. [PDF]

Calcif Tissue Int
Falsetti I, Palmini G, Donati S, Aurilia C, Zonefrati R, Di Filippo L, Giustina A, Giannini S, Arcidiacono GP, Iantomasi T, Lazzerini D, Joos-Vandewalle P, Lee C, Brandi ML.   +13 more
europepmc   +1 more source

ERBB3 and NGFR mark a distinct skeletal muscle progenitor cell in human development and hPSCs

Nature Cell Biology, 2017
Michael R Hicks, Julia Hiserodt, Katrina I. Paras, W. Fujiwara, Ascia Eskin, M. Jan, Haibin Xi, C. Young, D. Evseenko, S. Nelson, M. Spencer, B. V. Handel, A. Pyle   +12 more
semanticscholar   +1 more source

Ufmylation‐Deficient DDRGK1 Ameliorates Obesity by Inhibiting FASN‐Mediated Adipocyte Lipogenesis

Advanced Science, EarlyView.
DDRGK1 regulates de novo lipogenesis via stabilization of fatty acid synthase (FASN). DDRGK1‐mediated UFMylation of FASN prevents its ubiquitin–proteasomal degradation. Reduced DDRGK1 expression or mutation at the key UFMylation site enhances FASN degradation and suppresses fatty acid synthesis (FAS), resulting in smaller adipocytes and improved ...
Yin Li, Tangjun Zhou, Xiao Yang, Kewei Rong, Xiankun Cao, Lei Shi, Xin Wang, Hongjin Wan, Lei Cui, Kexin Liu, Tong Xing, Hang Zhang, Chen Zhao, Tingxian Guo, Peixiang Ma, Jie Zhao, An Qin   +16 more
wiley   +1 more source

Chronic and acute mediators of passive viscoelasticity in human skeletal muscle fibres. [PDF]

Exp Physiol
Privett GE, Ricci AW, Needham KW, Callahan DM.   +3 more
europepmc   +1 more source

Bioinspired Tissue Transparency: Achieving Sclera‐to‐Cornea Transplantation

Advanced Science, EarlyView.
A bioinspired decellularization‐compression‐locking tactic (DCLT) is developed to transform human sclerae into transparent corneal substitutes. These clear, robust, and pro‐regenerative substitutes are capable of repairing complex corneal injuries, including chemical burns, keratoconus, and penetrating wounds, demonstrating their clinical potential to ...
Xiuli Sun, Long Zhao, Zhen Shi, Jingting Wang, Shang Yang, Xia Qi, Hengrui Zhang, Ting Wang, Weiyun Shi   +8 more
wiley   +1 more source

Sex differences in human skeletal muscle fiber types and the influence of age, physical activity, and muscle group: A systematic review and meta-analysis. [PDF]

Physiol Rep
James JJ, Mellow ML, Bueckers EP, Gutsch SB, Wrucke DJ, Pearson AG, Smith AE, Hunter SK.   +7 more
europepmc   +1 more source

Mendelian Randomization and Double Machine Learning Modeling Reveal Brain Imaging‐Derived Phenotypes as Functional Contributors to 18 Autoimmune Inflammatory Diseases

Advanced Science, EarlyView.
This schematic integrates the eight statistically significant causal relationships identified between 1,366 brain imaging‐derived phenotypes (IDPs) and 18 autoimmune inflammatory diseases (AIDs). Arrows indicate the direction of causality inferred from bidirectional two‐sample MR analyses.
Jinbin Chen, Xin Wang, Haifeng Ding, Bosheng Zheng, Keni Zeng, Chuying Hu, Jiayi Liu, Xiao Zhu, Haibing Yu   +8 more
wiley   +1 more source

Integrated fibre-specific methylome and proteome profiling of human skeletal muscle across males and females with fibre-type deconvolution. [PDF]

Skelet Muscle
Palmer AS, García-Domínguez E, Taylor MF, Garnham A, Seale K, Steele JR, Lee HC, Schittenhelm RB, Eynon N.   +8 more
europepmc   +1 more source

Role of insulin in the regulation of human skeletal muscle protein synthesis and breakdown: a systematic review and meta-analysis

Diabetologia, 2015
H. Abdulla, Kenneth Smith, P. Atherton, I. Idris   +3 more
semanticscholar   +1 more source