Future research directions to identify risks and mitigation strategies for neurostructural, ocular, and behavioral changes induced by human spaceflight: A NASA-ESA expert group consensus report [PDF]
Frontiers in Neural Circuits, 2022 A team of experts on the effects of the spaceflight environment on the brain and eye (SANS: Spaceflight-Associated Neuro-ocular Syndrome) was convened by NASA and ESA to (1) review spaceflight-associated structural and functional changes of the human ...
Rachael D. Seidler +6 more
doaj +5 more sources
Articular cartilage loss is an unmitigated risk of human spaceflight [PDF]
npj MicrogravityMicrogravity and space radiation are hazards of spaceflight that have deleterious effects on articular cartilage. Since it is not widely monitored or protected through dedicated countermeasures, articular cartilage loss is an unmitigated risk of human ...
John G. Hardy
doaj +5 more sources
Ground-Based Analogs for Human Spaceflight [PDF]
Frontiers in Physiology, 2020 This mini-review provides an updated summary of various analogs for adaptations of humans to the microgravity of space. Microgravity analogs discussed in this paper include dry immersion, wet immersion, unilateral lower-extremity limb suspension, head ...
Meenakshi Pandiarajan, Alan R. Hargens
doaj +6 more sources
Estimating medical risk in human spaceflight. [PDF]
NPJ Microgravity, 2022 NASA and commercial spaceflight companies will soon be retuning humans to the Moon and then eventually sending them on to Mars. These distant planetary destinations will pose new risks—in particular for the health of the astronaut crews.
Antonsen EL +7 more
europepmc +6 more sources
Shallow metabolic depression and human spaceflight: a feasible first step. [PDF]
J Appl Physiol (1985), 2020 Synthetic torpor is an induced state of deep metabolic depression (MD) in an organism that does not naturally employ regulated MD. If applied to spaceflight crewmembers, this metabolic state may theoretically mitigate numerous biological and logistical ...
Regan MD +6 more
europepmc +3 more sources
High-Intensity Interval Training: A Potential Exercise Countermeasure During Human Spaceflight. [PDF]
Front Physiol, 2019 High-intensity interval training (HIT) is an effective approach for improving a range of physiological markers associated with physical fitness. A considerable body of work has demonstrated substantial improvements in cardiorespiratory fitness following ...
Hurst C, Scott JPR, Weston KL, Weston M.
europepmc +4 more sources
The human biology of spaceflight [PDF]
American Journal of Human BiologyTo expand the human exploration footprint and reach Mars in the 2030s, we must explore how humans survive and thrive in demanding, unusual, and novel ecologies (i.e., extreme environments).
Mallika S. Sarma, M. Shelhamer
semanticscholar +4 more sources
NASA Space Flight Human-System Standard: enabling human spaceflight missions by supporting astronaut health, safety, and performance. [PDF]
NPJ Microgravity, 2023 The purpose of this paper is to describe NASA’s approach to establishing and maintaining a set of Agency-level Space Flight Human System Standards managed by the Office of the Chief Health and Medical Officer (OCHMO) at NASA that enables space flight ...
Childress SD, Williams TC, Francisco DR.
europepmc +2 more sources
Microbiome for Mars: surveying microbiome connections to healthcare with implications for long-duration human spaceflight, virtual workshop, July 13, 2020. [PDF]
Microbiome, 2021 The inaugural “Microbiome for Mars” virtual workshop took place on July 13, 2020. This event assembled leaders in microbiome research and development to discuss their work and how it may relate to long-duration human space travel.
LaPelusa M +15 more
europepmc +2 more sources