The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight. [PDF]
Science, 2019 What to expect after a year in space Space is the final frontier for understanding how extreme environments affect human physiology. Following twin astronauts, one of which spent a year-long mission on the International Space Station, Garrett-Bakelman et
Garrett-Bakelman FE +81 more
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Microbiology of human spaceflight: microbial responses to mechanical forces that impact health and habitat sustainability. [PDF]
Microbiol Mol Biol RevSUMMARY Understanding the dynamic adaptive plasticity of microorganisms has been advanced by studying their responses to extreme environments. Spaceflight research platforms provide a unique opportunity to study microbial characteristics in new extreme ...
Nickerson CA +9 more
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The scientific case for human spaceflight [PDF]
Astronomy and Geophysics, 2001 Ian Crawford and Sarah Dunkin report on discussion at the National Astronomy Meeting in Cambridge in April, which marked two key dates in the history of human spaceflight, as well as looking forward to the challenges that will demand human intelligence and ingenuity in space in future.
Ian Crawford, S. K. Dunkin
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Neuromuscular Electrical Stimulation as a Potential Countermeasure for Skeletal Muscle Atrophy and Weakness During Human Spaceflight. [PDF]
Front Physiol, 2019 Human spaceflight is associated with a substantial loss of skeletal muscle mass and muscle strength. Neuromuscular electrical stimulation (NMES) evokes involuntary muscle contractions, which have the potential to preserve or restore skeletal muscle mass ...
Maffiuletti NA +3 more
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Spatial multi-omics of human skin reveals KRAS and inflammatory responses to spaceflight [PDF]
Nature CommunicationsSpaceflight can change metabolic, immunological, and biological homeostasis and cause skin rashes and irritation, yet the molecular basis remains unclear.
Jiwoon Park +23 more
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Effects of Spaceflight on Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Structure and Function. [PDF]
, 2019 With extended stays aboard the International Space Station (ISS) becoming commonplace, there is a need to better understand the effects of microgravity on cardiac function. We utilized human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs)
Agrawal +30 more
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Spaceflight Standard Measures is a multidisciplinary study that systematically monitors risks to astronaut health and performance [PDF]
npj MicrogravitySpaceflight Standard Measures is an integrated research study designed to characterize how spaceflight affects the health and performance of astronauts. Standardizing the research methods allows for robust monitoring of individuals and allows comparison ...
John G. Hardy +3 more
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Evaluating the effect of spaceflight on the host–pathogen interaction between human intestinal epithelial cells and Salmonella Typhimurium [PDF]
npj Microgravity, 2021 Spaceflight uniquely alters the physiology of both human cells and microbial pathogens, stimulating cellular and molecular changes directly relevant to infectious disease.
Jennifer Barrila +24 more
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Biofilms: from the cradle of life to life support [PDF]
npj Biofilms and MicrobiomesBiofilms are intricately associated with life on Earth, enabling functions essential to human and plant systems, but their susceptibility to spaceflight stressors and functional disruption in space remains incompletely understood.
Katherine J. Baxter +22 more
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Introducing the Concept of Exercise Holidays for Human Spaceflight - What Can We Learn From the Recovery of Bed Rest Passive Control Groups. [PDF]
Front Physiol, 2022 Ekman R +5 more
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