Results 51 to 60 of about 5,103 (239)

The Politics of Heroes’ Body: Ethnographying the Training of Foreign Astronauts in Russia

Corpus Mundi, 2020
If the literature in the history of the Soviet space program is extremely prolific since the 1960s, including regarding cosmonaut embodiment, a lack remains regarding the contemporary reality of human spaceflight in Russia.
Julie Patarin-Jossec
doaj   +1 more source

Artificial Intelligence Frameworks to Detect and Investigate the Pathophysiology of Spaceflight Associated Neuro-Ocular Syndrome (SANS)

Brain Sciences, 2023
Spaceflight associated neuro-ocular syndrome (SANS) is a unique phenomenon that has been observed in astronauts who have undergone long-duration spaceflight (LDSF).
Joshua Ong, Ethan Waisberg, Mouayad Masalkhi, Sharif Amit Kamran, Kemper Lowry, Prithul Sarker, Nasif Zaman, Phani Paladugu, Alireza Tavakkoli, Andrew G. Lee   +9 more
doaj   +1 more source

Human spaceflight: to infertility and beyond

International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 2019
Garrett-Bakelman FE et al, demonstrated a spectrum of molecular and physiological changes attributed to spaceflight in their recently published “NASA Twins Study”.1 During his 340 days in space onboard the International Space Station (ISS), one of a pair of monozygotic twins was not only challenged by noise, isolation, hypoxia, and alterations in the ...
Walter Cardona Maya, Stefan S. du Plessis   +1 more
openaire   +3 more sources

Direct RNA sequencing of astronaut blood reveals spaceflight-associated m6A increases and hematopoietic transcriptional responses

Nature Communications
The advent of civilian spaceflight challenges scientists to precisely describe the effects of spaceflight on human physiology, particularly at the molecular and cellular level.
Kirill Grigorev, Theodore M. Nelson, Eliah G. Overbey, Nadia Houerbi, JangKeun Kim, Deena Najjar, Namita Damle, Evan E. Afshin, Krista A. Ryon, Jean Thierry-Mieg, Danielle Thierry-Mieg, Ari M. Melnick, Jaime Mateus, Christopher E. Mason   +13 more
doaj   +1 more source

Simulated spaceflight-induced cardiac remodeling is modulated by gut microbial-derived trimethylamine N-oxide

iScience, 2023
Summary: Spaceflight is physically demanding and can negatively affect astronauts’ health. It has been shown that the human gut microbiota and cardiac function are affected by spaceflight and simulated spaceflight.
Zizhong Liu, Gui Luo, Ruikai Du, Guanghan Kan, Xuan Han, Guohui Zhong, Wenjuan Xing, Ying Cui, Weijia Sun, Jianwei Li, Yuheng Li, Dingsheng Zhao, Xinxin Yuan, Xiaoyan Jin, Yanping Han, Huiyuan Sun, Shukuan Ling, Yingxian Li   +17 more
doaj  

Human hypoxia models in aerospace medicine: Potential applications for human pharmacological research

British Journal of Clinical Pharmacology, EarlyView.
Aerospace medicine required controlled terrestrial models to investigate influences of altered atmosphere conditions, such as hypoxia, on human health and performance. These models could potentially be expanded to encompass disease conditions or treatment targets regulated through hypoxia or hypercapnia.
Titiaan E. Post, Cayla Denney, Adam Cohen, Jens Jordan, Ulrich Limper   +4 more
wiley   +1 more source

Feasibility of dried blood spot collection for caffeine pharmacokinetic studies in microgravity: Insights from parabolic flight campaigns

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Therapeutic drug monitoring for astronauts faces limitations in conventional blood sampling and sample management onboard the international space station. Here, we explore the feasibility of dried blood spot (DBS) collection during parabolic flights (PF) to overcome these constraints.
Audrey Derobertmasure, Li Shean Toh, Céline Verstuyft, Srboljub Lukic, Christelle De Sousa Carvalho, Raphaël Couronné, Marie Beauvalet, Stéphanie Chhun, Pierre Boutouyrie   +8 more
wiley   +1 more source

Evaluating Investment in Space Programs: A Case for Theoretical Pluralism

Financial Accountability &Management, EarlyView.
ABSTRACT A perennial question repeatedly asked since the early Mercury (USA) and Salyut (then Soviet Union) space programs has been variations on the theme of “how can the cost of space exploration be justified?” This question—which in broad terms constitutes the research question considered in this paper—continues to be directed toward space agencies ...
Basil P. Tucker, Hank C. Alewine
wiley   +1 more source

The futuristic manifolds of REM sleep

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Since one of its first descriptions 70 years ago, rapid eye movement sleep has continually inspired and excited new generations of sleep researchers. Despite significant advancements in understanding its neurocircuitry, underlying mechanisms and microstates, many questions regarding its function, especially beyond the early neurodevelopment ...
Liborio Parrino, Ivana Rosenzweig
wiley   +1 more source

Is sleep affected after microgravity and hypergravity exposure? A pilot study

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Sleep is known to be affected in space travel and in residents of the international space station. But little is known about the direct effects of gravity changes on sleep, if other factors, such as sleep conditions, are kept constant. Here, as a first exploration, we investigated sleep before and after exposure to short bouts of microgravity ...
Barbara Le Roy, Aurore Jouvencel, Anika Friedl‐Werner, Ludmila Renel, Youcef Cherchali, Raouf Osseiran, Ernesto Sanz‐Arigita, Jean‐René Cazalets, Etienne Guillaud, Ellemarije Altena   +9 more
wiley   +1 more source