Results 71 to 80 of about 5,103 (239)

Author comment: Optimizing human performance in extreme environments through precision medicine: From spaceflight to high-performance operations on Earth — R1/PR6 [PDF]

, 2023
Michael A. Schmidt
openalex   +2 more sources

Confined spaces in space: Cerebral implications of chronic elevations of inspired carbon dioxide and implications for long‐duration space travel

Experimental Physiology, EarlyView.
Abstract Cerebrovascular regulation is critically dependent upon the arterial partial pressure of carbon dioxide (PaCO2${P_{{\mathrm{aC}}{{\mathrm{O}}_{\mathrm{2}}}}}$), owing to its effect on cerebral blood flow, tissue PCO2${P_{{\mathrm{C}}{{\mathrm{O}}_{\mathrm{2}}}}}$, tissue proton concentration, cerebral metabolism and cognitive and neuronal ...
Jay M. J. R. Carr, Philip N. Ainslie, Trevor Day   +2 more
wiley   +1 more source

The search for the ultimate exercise countermeasure to preserve crew health and ensure mission success in long‐duration spaceflight

Experimental Physiology, EarlyView.
Abstract The current understanding of crew health maintenance is founded upon decades of physiological research conducted in terrestrial spaceflight analogues and in low Earth orbit, particularly on the International Space Station. However, as we progress towards the Lunar Gateway and interplanetary missions, it is imperative that the tools employed to
Rodrigo Fernandez‐Gonzalo, Stefan Schneider, Martina Heer, Anna‐Maria Liphardt   +3 more
wiley   +1 more source

Establishing a method for the cryopreservation of viable peripheral blood mononuclear cells in the International Space Station

npj Microgravity
The analysis of cells frozen within the International Space Station (ISS) will provide crucial insights into the impact of the space environment on cellular functions and properties.
Hiroto Ishii, Rin Endo, Sanae Hamanaka, Nobuyuki Hidaka, Maki Miyauchi, Naho Hagiwara, Takahisa Miyao, Tohru Yamamori, Tatsuya Aiba, Nobuko Akiyama, Taishin Akiyama   +10 more
doaj   +1 more source

The Impact of Spaceflight and Microgravity on the Human Islet-1+ Cardiovascular Progenitor Cell Transcriptome [PDF]

, 2021
Victor Camberos, Jonathan Baio, Ana Mandujano, Aida F. Martinez, Leonard L. Bailey, Nahidh Hasaniya, Mary Kearns‐Jonker   +6 more
openalex   +1 more source

50% body weight loading reduces stature increases and lumbar disc expansion from 4 h hyper‐buoyancy floatation versus 15 min sitting upright

Experimental Physiology, EarlyView.
Abstract Microgravity is associated with stature increases, back pain and post‐flight intervertebral disc (IVD) herniation. This study aims to determine whether 30 s seated 50% body weight (BW) axial loading is comparable to 15 min sitting upright in 1 g upon changes in stature, anterior lumbar IVD height (via ultrasound), passive vertebral stiffness ...
David Marcos‐Lorenzo, Christina Lysandrou, Laura Sudres, Alfonso Gil‐Martinez, Jaap Swanenburg, James Edward Clark, David Andrew Green   +6 more
wiley   +1 more source

Human Assisted Science at Venus: Venus Exploration in the New Human Spaceflight Age [PDF]

, 2021
N. R. Izenberg, R. L. McNutt, Kirby Runyon, P. K. Byrne, Alexander William Macdonald   +4 more
openalex   +1 more source

Effects of the angle of head‐down tilt on dynamic cerebral autoregulation during combined exposure to cephalad fluid shift and mild hypercapnia

Experimental Physiology, EarlyView.
Abstract Astronauts experience combined exposure to a cephalad fluid shift and mild hypercapnia during space missions, potentially contributing to health problems. Such combined exposure may weaken dynamic cerebral autoregulation. The magnitude of cephalad fluid shift varies between individuals, and dynamic cerebral autoregulation may be affected more ...
Tomokazu Kato, Yojiro Ogawa, Ken‐ichi Iwasaki   +2 more
wiley   +1 more source

NASA Space Flight Human-System Standard: enabling human spaceflight missions by supporting astronaut health, safety, and performance. [PDF]

NPJ Microgravity, 2023
Childress SD, Williams TC, Francisco DR.
europepmc   +1 more source

An experimentally informed computational model of neurovestibular adaptation to altered gravity

Experimental Physiology, EarlyView.
Abstract Transitions to altered gravity environments result in acute sensorimotor impairment for astronauts, leading to serious mission and safety risks in the crucial first moments in a new setting. Our understanding of the time course and severity of impairment in the early stages of adaptation remains limited and confounded by unmonitored head ...
Victoria G. Kravets, Torin K. Clark
wiley   +1 more source