Equine herpesvirus 1 bridles T lymphocytes to reach its target organs [PDF]
Equine herpesvirus 1 (EHV1) replicates in the respiratory epithelium and disseminates through the body via a cell-associated viremia in leukocytes, despite the presence of neutralizing antibodies. "Hijacked" leukocytes, previously identified as monocytic
Azab, Walid +7 more
core +1 more source
Human T-lymphotropic virus type 1 (HTLV-1) and innate immunity
Human T-cell lymphotropic virus type 1 (HTLV-1) is a T lymphotropic human retrovirus that causes adult T-cell leukemia/lymphoma (ATL) and is associated with immunological disorders such as HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP).
Tomoo Sato +4 more
openaire +2 more sources
Crusted (Norwegian) scabies as a strong marker of adult T‐cell leukemia/lymphoma in HTLV‐1 infection
Key Clinical Message We present a rare case of crusted scabies in an human T‐cell lymphotropic virus type 1 (HTLV‐1) infected woman prior to onset of adult T‐cell leukemia/lymphoma (ATL).
César Bimbi +2 more
doaj +1 more source
Epidemiology of Human T-cell Lymphotropic Virus Type 1 Infection in Blood Donors, Israel
The prevalence of infection with human T-cell lymphotropic virus type 1 (HTLV-1) in blood donors from Israel is 1 infection/100,000 persons. In donors originating from Eastern Europe, the Middle East, and Latin America, prevalences are 7.7, 14.6, and 20 ...
Shmuel Stienlauf +5 more
doaj +1 more source
The evolution of sex-specific virulence in infectious diseases [PDF]
Fatality rates of infectious diseases are often higher in men than women. Although this difference is often attributed to a stronger immune response in women, we show that differences in the transmission routes that the sexes provide can result in ...
A Sasaki +57 more
core +1 more source
Pathways of cell-cell transmission of HTLV-1
The deltaretroviruses human T-cell lymphotropic virus type 1 (HTLV-1) and human T-cell lymphotropic virus type 2 (HTLV-2) have long been believed to differ from retroviruses in other genera by their mode of transmission.
Claudine ePique +2 more
doaj +1 more source
Seroprevalence of HTLV-1 and HTLV-2 amongst mothers and children in Malawi within the context of a systematic review and meta-analysis of HTLV seroprevalence in Africa [PDF]
OBJECTIVES: Human T‐lymphotropic virus (HTLV)‐1 causes T‐cell leukaemia and myelopathy. Together with HTLV‐2, it is endemic in some African nations. Seroprevalence data from Malawi are scarce, with no reports on associated disease incidence.
Bland, M +7 more
core +1 more source
WIP1 deficiency inhibits HTLV-1 Tax oncogenesis: novel therapeutic prospects for treatment of ATL?
Attenuation of p53 activity appears to be a major step in Human T-lymphotropic virus type 1 (HTLV-1) Tax transformation. However, p53 genomic mutations are late and rather infrequent events in HTLV-1 induced Adult T cell leukemia (ATL). The paper by Zane
Gillet Nicolas +3 more
doaj +1 more source
Gem-induced cytoskeleton remodeling increases cellular migration of HTLV-1-infected cells, formation of infected-to-target T-cell conjugates and viral transmission [PDF]
Efficient HTLV-1 viral transmission occurs through cell-to-cell contacts. The Tax viral transcriptional activator protein facilitates this process. Using a comparative transcriptomic analysis, we recently identified a series of genes up-regulated in HTLV-
Afonso, PV +7 more
core +1 more source
The first discovered human retrovirus, Human T-Lymphotropic Virus type 1 (HTLV-1), is responsible for an aggressive form of T cell leukemia/lymphoma.
Eléonore Pérès +6 more
doaj +1 more source

