Results 191 to 200 of about 8,929,565 (386)

Trafficking of people. Human trafficking [PDF]

open access: yesObstetrics & Gynecology International Journal, 2018
openaire   +2 more sources

Cytokine Engineering Approaches for Regenerative Medicine

open access: yesAdvanced Therapeutics, EarlyView.
Engineered cytokines represent a powerful strategy to promote tissue repair and regeneration by precisely modulating immune responses. This review highlights recent advances in cytokine engineering, including strategies to enhance half‐life, improve tissue and cell targeting, and control receptor signaling.
Shiyi Li, Wenhao You, Mikaël M. Martino
wiley   +1 more source

Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy

open access: yesAdvanced Therapeutics, EarlyView.
This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar   +7 more
wiley   +1 more source

Mutations in ARFGEF2 implicate vesicle trafficking in neural progenitor proliferation and migration in the human cerebral cortex [PDF]

open access: bronze, 2003
Volney Sheen   +11 more
openalex   +1 more source

Enhancing the Effectiveness of Chemotherapy in Osteosarcoma by Targeting Tumour‐Associated Macrophages (TAMs) through STING Activation

open access: yesAdvanced Therapeutics, EarlyView.
Osteosarcoma isa highly aggressive bone cancer with an immunosuppressive tumor microenvironment that limits immunotherapy. This study explores STING pathway activation to reprogram tumor‐associated macrophages into a tumoricidal M1‐like phenotype and enhance doxorubicin efficacy. Results show that doxorubicin alone failed to activate the STING pathway,
Jordan C. O'Donoghue   +3 more
wiley   +1 more source

Oligomerization and Trafficking of the Human Dopamine Transporter [PDF]

open access: hybrid, 2003
Gonzalo E. Torres   +6 more
openalex   +1 more source

Transnational Trafficking, Law Enforcement and Victim Protection: A Middleman Trafficker's Perspective [PDF]

open access: yes
We explore three hitherto poorly understood characteristics of the human trafficking market – the cross-border ease of mobility of traffickers, the relative bargaining strength of traffickers and final buyers, and the elasticity of buyers' demand.
Akee, Randall K. Q.   +3 more
core  

NAD+‐Boosters Improve Mitochondria Quality Control In Parkinson's Disease Models Via Mitochondrial UPR

open access: yesAdvanced Science, EarlyView.
Treatment of MPTP‐incubated cells with NAD+‐boosters increase the UPRmt/mitophagy‐related mitochondria quality control (MQC). Disturbed plasma UPRmt‐mitophagy‐mediated MQC profiles in PD patient samples. NMN inhibits motor deficit and forestalls neuropathology phenotypes of PD mice, which is required the atf4‐medicated UPRmt pathway.
Shuoting Zhou   +16 more
wiley   +1 more source

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