Results 261 to 270 of about 8,929,565 (386)

The Global Diffusion of Law: Transnational Crime and the Case of Human Trafficking

open access: yesInternational Organization, 2018
B. Simmons   +2 more
semanticscholar   +1 more source

Tsg101 Control of Human Immunodeficiency Virus Type 1 Gag Trafficking and Release

open access: green, 2003
Arthur J. Goff   +3 more
openalex   +1 more source

RAB5A Promotes Active Fluid Wetting by Reprogramming Breast Cancer Spheroid Mechanics

open access: yesAdvanced Science, EarlyView.
RAB5A‐mediated unjamming enhances active wetting through distinct biomechanical processes: a) upregulation of specific integrin subunits, enhanced focal adhesions kinetics and activity; b) supracellular organization relying on nanoscale integrin clustering, and the formation of a stiff and collective actin cable; and c) softening of the spheroid core ...
Grégoire Lemahieu   +19 more
wiley   +1 more source

STING COPII ER Export Trafficking and Signaling Primed by Phosphorylation Switches

open access: yesAdvanced Science, EarlyView.
This schematic outlines STING trafficking and signaling via coat protein II (COPII)‐mediated endoplasmic reticulum (ER) export. Following cyclic GMP‐AMP (cGAMP) stimulation, TANK‐binding kinase 1 (TBK1) activates on COPII vesicles, partially dissociating into the cytosol to phosphorylate ER‐localized STING, creating pSGME/pFS COPII‐sorting motifs ...
Yanan Nan   +10 more
wiley   +1 more source

Sequence‐ and Docking‐Site‐Dependent Contributions to Multi‐Site Phosphorylation of an Intrinsically Disordered MAPK Substrate

open access: yesAdvanced Science, EarlyView.
Real‐time NMR spectroscopy is used to study JNK1‐dependent phosphorylation of the intrinsically disordered substrate JIP1, revealing eleven phosphosites with distinct phosphorylation efficiencies. The site‐specific phosphorylation rates are shown to be determined by both the sequence position of the phosphosites relative to the two kinase docking site ...
Thibault Orand   +7 more
wiley   +1 more source

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