Results 181 to 190 of about 29,482,845 (310)

Modulation of sebocyte function in acne: A pathway‐inclusive review

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Acne is multifactorial, with the sebocyte acting as a central immunometabolic hub linking lipogenic, inflammatory, hormonal and barrier pathways. Mapping established and investigational therapies onto this sebocyte‐centred model offers a mechanism‐based framework that complements existing treatment paradigms and may guide more targeted, antibiotic ...
Christos C. Zouboulis, Apostolos Pappas, Katja Martin, Mauro Picardo   +3 more
wiley   +1 more source

Advances and prospects of 3D air-liquid interface cultured middle ear epithelial cells and inner ear organoids in otologic diseases. [PDF]

Front Bioeng Biotechnol
Gu L, Du M, Zhang K, Wu Y, Zheng T, Zheng Q, Li B.   +6 more
europepmc   +1 more source

Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development

Journal of Anatomy, Volume 246, Issue 4, Page 616-630, April 2025.
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah, Anna Wilsdon, Aseel Abbad, Sophie Rochette, Frances Bu'Lock, Asma Ali Saed, Marc‐Phillip Hitz, J. David Brook, Siobhan Loughna   +8 more
wiley   +1 more source

A single-nucleus transcriptomic atlas of human inner ear development. [PDF]

Nat Neurosci
van der Valk WH, Udayappan SD, van Beelen ESA, Goveia J, Beatovic A, Moisse M, Menafra R, de Groot JCMJ, Koehler KR, van Benthem PPG, Locher H.   +10 more
europepmc   +1 more source

Extracellular vesicles derived from human vestibular schwannomas associated with poor hearing damage cochlear cells.

Neuro-Oncology, 2016
V. Soares, Nadia A. Atai, Takeshi Fujita, Sonam Dilwali, Sarada Sivaraman, L. D. Landegger, F. Hochberg, C. Oliveira, F. Bahmad, X. Breakefield, K. Stanković   +10 more
semanticscholar   +1 more source

Biomaterials for Reconstructive Treatment of Peri‐Implantitis

Journal of Periodontal Research, EarlyView.
Reconstructive therapy should be implemented in contained defects. Various bone filler materials with or without a barrier membrane and/or adjunctive biologics may be applied. ABSTRACT Peri‐implantitis is a pathological condition affecting the tissues surrounding dental implants, marked by inflammation of the peri‐implant connective tissue and ...
Ausra Ramanauskaite, Anton Sculean, Emilio A. Cafferata, Frank Schwarz   +3 more
wiley   +1 more source

Thirty Years of Autologous Platelet Concentrates: From Platelet‐Rich Plasma to Platelet‐Rich Fibrin

Journal of Periodontal Research, EarlyView.
This review highlights the 30 years of evolution of APCs, with a focus on their clinical applications and recent technological advancements. ABSTRACT Nearly three decades have now passed since autologous platelet concentrates (APCs) were introduced into clinical practice.
Richard J. Miron, Nathan E. Estrin, Paras Ahmad, Nima Farshidfar, Masako Fujioka‐Kobayashi, Yufeng Zhang, Mario Romandini, Reinhard Gruber   +7 more
wiley   +1 more source

The Keystone‐Pathogen Hypothesis Updated: The Role of Porphyromonas gingivalis in Periodontitis

Journal of Periodontal Research, EarlyView.
Porphyromonas gingivalis orchestrates a coordinated manipulation of immune and inflammatory responses in periodontal tissues which leads to the generation of a dysbiotic, subgingival biofilm community, and progression of periodontitis. The type 9 secretion system, lipid A modification, and the formation of outer membrane vesicles are important ...
Mike A. Curtis, James A. Garnett, Richard P. Darveau   +2 more
wiley   +1 more source

Bridging mechanistic evidence and clinical perspectives: traditional Chinese medicine in Menière's disease. [PDF]

Front Neurol
Ye S, Zhu Z.
europepmc   +1 more source

Characterization of pulse amplitude and pulse rate modulation for a human vestibular implant during acute electrical stimulation

Journal of Neural Engineering, 2016
T. A. K. Nguyen, J. DiGiovanna, S. Cavuscens, M. Ranieri, N. Guinand, R. van de Berg, J. Carpaneto, H. Kingma, J. Guyot, S. Micera, A. Fornos   +10 more
semanticscholar   +1 more source