Results 161 to 170 of about 23,454,763 (293)

Sodium Ions Affect GPR17 Conformational States and Functionality

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Sodium is an allosteric modulator of several class‐A GPCR regulating active versus inactive conformation state and may be a critical issue for the optimization of crystallization procedures. Herein, the role of Na+ in the regulation of GPR17 conformational states was studied through MD simulations of GPR17 wild‐type and mutated on two ...
Luca Palazzolo, Simona Daniele, Davide Bianchi, Lara Russo, Stefano Capaldi, Maria Letizia Trincavelli, Ivano Eberini   +6 more
wiley   +1 more source

Brain‐Inspired Neuromorphic Device for Artificial Intelligent Robots Applications

SmartBot, EarlyView.
Brain‐inspired neuromorphic devices mimic biological systems to provide an efficient hardware foundation for embodied intelligent robotics. This review explores the material systems and corresponding computing architectures of neuromorphic devices that support low‐power perception, adaptive learning, and real‐time decision‐making.
Jiachen Han, Zheng Wang, Tianyu Wang, Jialin Meng   +3 more
wiley   +1 more source

How We Simulate Nanopores

Small Methods, EarlyView.
Nanopore technology has revolutionized single‐molecule sensing, yet it suffers from an inherent interpretive challenge. Molecular dynamics has emerged as a go‐to method for determining the relationship between the structure of translocating molecules and the nanopore current signals.
Behzad Mehrafrooz, Xavier Mleziva, Meng Xu, Melika Shekari, Christopher Maffeo, Aleksei Aksimentiev   +5 more
wiley   +1 more source

Basic Vestibular Anatomy and Physiology

, 1999
The vestibular system senses the movement and the inclination of the head. The adequate stimulus is head acceleration, angular or linear.
Michael Halfflflgyi, MD
core  

Subjective Visual Vertical Can be an Effective Tool to Evaluate Vestibular Function of Stapedotomy

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective To investigate if the subjective visual vertical/horizontal (SVV/SVH) can be used to evaluate the otolith organ of otosclerosis and stapedotomy. Design A total of 19 patients who were diagnosed with otosclerosis and underwent surgical treatment in our hospital were collected.
Tao Jiang, Juan Zheng, Wen‐Yan Li
wiley   +1 more source

Unveiling Otolith Mystery: Contemporary Testing Approaches and Their Clinical Significance

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Otolith is a critical component of the peripheral vestibular system responsible for detecting linear acceleration. Dysfunction of the otolith organs can lead to vertigo, balance disturbances, and gaze instability. By elucidating the physiological foundations and evaluating both current and emerging methods for assessing otolith ...
Shun Zhou, E Tian, Hua‐Jing Yang, Jun Wang, Zhao‐Qi Guo, Jing‐Yu Chen, Wan‐Di Xu, Jia‐Qi Guo, Zhang‐Hong Zhou, Shi‐Yu Shi, Xi‐Xi Yu, Xin‐Bo Gao, Ni Zhai, Xin Ma, Qing Zhang, Yi‐Sheng Lu, Su‐Lin Zhang   +16 more
wiley   +1 more source

Neuro-otological and psychiatric abnormalities in a community sample of people with dizziness: a blind, controlled investigation

, 1998
Objectives—To determine neurootological and psychiatric abnormalities associated with complaints of dizziness in an epidemiological community sample of people of working age, and the extent of comorbidity between neuro-otological and psychiatric ...
Yardley, L., Burgneay, J., Luxon, L., Nazareth, I.   +3 more
core   +1 more source

Aging of vestibular function evaluated using correlational vestibular autorotation test

, 2014
Li-Chun Hsieh,1,2 Hung-Ching Lin,2,3 Guo-She Lee4,5 1Institute of Brain Science, School of Medicine, National Yang-Ming University, Taipei, Taiwan; 2Department of Otolaryngology, Mackay Memorial Hospital, Taipei, Taiwan; 3Department of Audiology and ...
Lin HC, Hsieh LC, Lee GS
core  

The Early Upper Palaeolithic in British caves: problems and potential Le Paléolithique supérieur ancien dans les grottes de Grande‐Bretagne : problèmes et potentiels

Journal of the Royal Anthropological Institute, EarlyView.
Recent years have seen landmark progress in our understanding of early Homo sapiens occupation of Europe, owing to new excavations and the application of new analytical methods. Research on British sites, however, continues to lag. This is because of limitations inherent in existing cave collections, and limited options for new fieldwork at known sites.
Robert Dinnis
wiley   +1 more source

125 years of exploration and research at Gough's Cave (Somerset, UK) 125 ans d'exploration et de recherches à Gough's Cave (Somerset, Royaume‐Uni)

Journal of the Royal Anthropological Institute, EarlyView.
Our understanding of the recolonization of northwest Europe in the period leading up to the Lateglacial Interstadial relies heavily on discoveries from Gough's Cave (Somerset, UK). Gough's Cave is the richest Late Upper Palaeolithic site in the British Isles, yielding an exceptional array of human remains, stone and organic artefacts, and butchered ...
Silvia M. Bello, Mark D. Lewis, Simon A. Parfitt   +2 more
wiley   +1 more source