Results 161 to 170 of about 35,182 (284)

Multivalent antibody‐based conjugates as new tools for tailored modulation of G protein–coupled receptors

open access: yesBritish Journal of Pharmacology, EarlyView.
The G protein–coupled receptor (GPCR) superfamily consists of the most common targets of approved drugs. Targeting GPCRs offers appealing avenues for therapeutic development. Antibodies and their fragments, such as single‐domain antibodies (VHHs or nanobodies), have emerged as useful alternatives to small molecule pharmacophores as building blocks in ...
Shivani Sachdev, Ross W. Cheloha
wiley   +1 more source

Neurodevelopmental Phenotypes and Brain Anomalies in Individuals With Heterozygous SEMA6A Variants

open access: yesClinical Genetics, EarlyView.
SEMA6A plays a role in cell migration and axon guidance in the developing central nervous system. Phenotypes seen in eleven individuals heterozygous for SEMA6A variants included developmental delay, intellectual disability, autism/autistic behaviors, behavioral abnormalities, attention disorders, hypotonia, and brain anomalies.
Evan Burchfiel   +27 more
wiley   +1 more source

Dental Splints in Dentoalveolar Trauma: An Overview of Public Healthcare Services in Brazil

open access: yesDental Traumatology, EarlyView.
ABSTRACT Background/Aim The prognosis of traumatized teeth might be influenced by the type and quality of the dental splint. This prospective observational study was aimed to evaluate the indications and quality of dental splints performed in a comprehensive public oral health service in the city of Uberlândia, Brazil.
Caroline Garcia Orsi   +6 more
wiley   +1 more source

The Place for Form in Wollheim's Lectures on Formalism and Pictorial Organization

open access: yesEuropean Journal of Philosophy, EarlyView.
Abstract At the time of his death, Richard Wollheim was writing a short book on Formalism and Pictorial Organization. Much of it, but by no means all of it, had been published before (it has come out posthumously in its entirety in late 2025). Here I do two things. First, I have provided a rather detailed exegesis concentrating on the parts of the book
Gary Kemp
wiley   +1 more source

Evaluation of physical, chemical, and color‐matching properties of monochromatic resin composites: An in vitro study

open access: yesEuropean Journal of Oral Sciences, EarlyView.
Abstract The objectives of this study are to evaluate, in vitro, the microhardness, sorption, solubility, color stability, and color‐matching ability of monochromatic resin composites: Palfique Omnichroma / Tokuyama (Mono1) and Vittra APS Unique / FGM (Mono2) compared with the conventional resin composite: Filtek Z250 XT / Solventum (Conv).
Ericka dos Santos Lopes   +5 more
wiley   +1 more source

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