Results 51 to 60 of about 80,836 (297)

Finding a Balance: A Systematic Review of the Biomechanical Effects of Vestibular Prostheses on Stability in Humans

Journal of Functional Morphology and Kinesiology, 2020
The vestibular system is located in the inner ear and is responsible for maintaining balance in humans. Bilateral vestibular dysfunction (BVD) is a disorder that adversely affects vestibular function.
Felix Haxby, Mohammad Akrami, Reza Zamani   +2 more
doaj   +1 more source

Learning to stand with unexpected sensorimotor delays

eLife, 2021
Human standing balance relies on self-motion estimates that are used by the nervous system to detect unexpected movements and enable corrective responses and adaptations in control.
Brandon G Rasman, Patrick A Forbes, Ryan M Peters, Oscar Ortiz, Ian Franks, J Timothy Inglis, Romeo Chua, Jean-Sébastien Blouin   +7 more
doaj   +1 more source

A mathematical model for top-shelf vertigo: the role of sedimenting otoconia in BPPV [PDF]

, 2003
Benign Paroxysmal Positional Vertigo (BPPV) is a mechanical disorder of the vestibular system in which calcite particles called otoconia interfere with the mechanical functioning of the fluid-filled semicircular canals normally used to sense rotation ...
Batchelor, Brandt, Brandt, Brandt, Brenner, Bronzino, Buckingham, Campos, Cooley, Curthoys, Dai, Damiano, Epley, Epley, Goldman, Hain, Happel, Hirschfeld, House, Howard A. Stone, Leal, Michael S. Weidman, Muller, O'Neill, Oghalai, Oman, Otsuka, Parnes, Rabbitt, Raphan, Robinson, Semont, Steinhausen, Suzuki, Timothy C. Hain, Todd M. Squires, Van Buskirk   +36 more
core   +3 more sources

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

Advanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang, Na Li, Yan Wang, Jing Zhang, Jiahui Liu, Lei Chen, Yongdong Song, Yurong Mu, Yuechen Han, Yafeng Lyu, Xiaofei Li, Hanyue Wang, Jing Wang, Yao Lu, Zhaomin Fan, Daogong Zhang, Haibo Wang   +16 more
wiley   +1 more source

HSV-1 not only in human vestibular ganglia but also in the vestibular labyrinth [PDF]

, 2001
Reactivation of herpes simplex virus type 1 (HSV-1) in the vestibular ganglion (VG) is the suspected cause of vestibular neuritis (VN). Recent studies reported the presence of HSV-1 DNA not only in human VGs but also in vestibular nuclei, a finding that ...
Arbusow, Viktor, Brandt, Thomas, Mascolo, Andrea, Strupp, Michael, Theil, Diethilde   +4 more
core   +1 more source

Sono‐Mechanogenetics: Linking Ultrasound Physics With Cellular Mechanobiology

Advanced Science, EarlyView.
Sono‐mechanogenetics links ultrasound physics with cellular mechanotransduction to enable noninvasive control of engineered biological systems. Acoustic forces generate distinct deformation modes that activate intracellular signaling pathways, which can be coupled to synthetic gene circuits to regulate diverse cellular functions, including gene ...
Yunjia Qu, Fan Wei, Chi Woo Yoon, Qifa Zhou, Yingxiao Wang   +4 more
wiley   +1 more source

Vestibular contribution to the planning of reach trajectories [PDF]

, 2018
Reaching for an object while simultaneously rotating induces Coriolis and centrifugal inertial forces on the arm that require compensatory actions to maintain accuracy.
Bockisch, Christopher, Haslwanter, Thomas   +1 more
core  

The Neuroanatomical Correlates of Training-Related Perceptuo-Reflex Uncoupling in Dancers [PDF]

, 2013
Sensory input evokes low-order reflexes and higher-order perceptual responses. Vestibular stimulation elicits vestibular-ocular reflex (VOR) and self-motion perception (e.g., vertigo) whose response durations are normally equal.
Hellyer, PJ, Nachev, P, Nigmatullina, Y, Seemungal, BM, Sharp, DJ   +4 more
core   +1 more source

Extent of Lymph Node Dissection for cStage I Siewert Type I/II Cancers Based on Lymph Node Metastasis Risk Stratification

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim The optimal surgical strategy and extent of lymph node (LN) dissection for clinical Stage I (cStage I) adenocarcinoma of the esophagogastric junction (AEG) remain controversial. This study aimed to evaluate surgical outcomes and clarify the prevalence and distribution of LN metastasis according to tumor characteristics in cStage I Siewert ...
Masayoshi Terayama, Akihiko Okamura, Tomoyuki Irino, Naoki Takahashi, Jun Kanamori, Yu Imamura, Masaru Hayami, Motonari Ri, Souya Nunobe, Masayuki Watanabe   +9 more
wiley   +1 more source

Dual-AAV vector-mediated expression of MYO7A improves vestibular function in a mouse model of Usher syndrome 1B

Molecular Therapy: Methods & Clinical Development, 2023
Usher syndrome is the most common cause of deafness-blindness in the world. Usher syndrome type 1B (USH1B) is associated with mutations in MYO7A. Patients with USH1B experience deafness, blindness, and vestibular dysfunction.
Samantha C. Lau, Mhamed Grati, Kevin Isgrig, Moaz Sinan, Kaitlyn R. Calabro, Jianliang Zhu, Yasuko Ishibashi, Zeynep Ozgur, Talah Wafa, Inna A. Belyantseva, Tracy Fitzgerald, Thomas B. Friedman, Sanford L. Boye, Shannon E. Boye, Wade W. Chien   +14 more
doaj   +1 more source