Results 91 to 100 of about 8,242 (199)

Review article: the human intestinal virome in health and disease [PDF]

Alimentary Pharmacology & Therapeutics, 2017
SummaryBackgroundThe human virome consists of animal‐cell viruses causing transient infections, bacteriophage (phage) predators of bacteria and archaea, endogenous retroviruses and viruses causing persistent and latent infections. High‐throughput, inexpensive, sensitive sequencing methods and metagenomics now make it possible to study the contribution ...
N. Davis, Simon R. Carding, Simon R. Carding, Lesley Hoyles   +3 more
openaire   +7 more sources

Commensal Viruses Promote Intestinal Stem Cell Regeneration Following Radiation Damage by Inhibiting Hyperactivation of RIG‐I and Notch Signals

Advanced Science, Volume 12, Issue 37, October 6, 2025.
Ionizing radiation disrupts gut virome and bacteriome. Gut commensal viruses protect against intestinal damage and promote stem cell regeneration by inhibiting hyperactivation of RIG‐I and Notch signaling in stem cells. Fecal virome transplantation (FVT) from healthy donors can serve as a potential therapeutic intervention by enriching phages targeting
Xiaotong Zhao, Yu Cai, Yujia Hou, Yanjin Wu, Tingting Wei, Lili Li, Zhaojun Duan, Xinran Lu, Jiahui Meng, Haitao Zhou, Qin Wang, Jinhan Wang, Chang Xu, Liqing Du, Saijun Fan, Feng Wang, Qiang Liu, Yang Liu   +17 more
wiley   +1 more source

The Human Virome Protein Cluster Database (HVPC): A Human Viral Metagenomic Database for Diversity and Function Annotation

Frontiers in Microbiology, 2018
Human virome, including those of bacteria (bacteriophages) have received an increasing attention recently, owing to the rapid developments in human microbiome research and the awareness of the far-reaching influence of microbiomes on health and disease ...
Ali H. A. Elbehery, Judith Feichtmayer, Dave Singh, Dave Singh, Christian Griebler, Li Deng   +5 more
doaj   +1 more source

Targeting gut microbiota and metabolites in cancer radiotherapy

Clinical and Translational Medicine, Volume 15, Issue 10, October 2025.
Radiotherapy (RT) efficacy and toxicity are influenced by gut microbiota and their metabolites. This review explores how probiotics, prebiotics, and microbial byproducts (e.g., short‐chain fatty acids [SCFAs]) mitigate radiation damage and enhance tumour radiosensitivity.
Shuling Ma, Xinpei Li, Shijie Shang, Zijun Zhai, Meng Wu, Qian Song, Dawei Chen   +6 more
wiley   +1 more source

The microbiome in cancer

iMeta, Volume 4, Issue 5, October 2025.
This comprehensive review elucidates the transformative role of the human microbiome in cancer biology, revealing innovative mechanistic insights into the intricate tumor–microbe interactions across diverse organ systems. This work highlights the clinical and translational value of novel microbiome‐based biomarkers for early detection, prognosis, and ...
Anqi Lin, Minying Xiong, Aimin Jiang, Lihaoyun Huang, Hank Z. H. Wong, Suyin Feng, Chunyan Zhang, Yu Li, Li Chen, Hao Chi, Pengpeng Zhang, Bicheng Ye, Hengguo Zhang, Nan Zhang, Lingxuan Zhu, Weiming Mou, Junyi Shen, Kailai Li, Wentao Xu, Haoxuan Ying, Cangang Zhang, Dongqiang Zeng, Jindong Xie, Xinpei Deng, Qi Wang, Jianying Xu, Wenjie Shi, Chang Qi, Chunrun Qu, Xufeng Huang, András Hajdu, Chaoqun Li, Changmin Peng, Xuanye Cao, Guangsheng Pei, Lin Zhang, Yujia Huo, Jiabao Xu, Antonino Glaviano, Attila Gábor Szöllősi, Sicheng Bian, Zhengrui Li, Hailin Tang, Bufu Tang, Zaoqu Liu, Jian Zhang, Kai Miao, Quan Cheng, Ting Wei, Shuofeng Yuan, Peng Luo   +50 more
wiley   +1 more source

Altered Phage‐Related Gene Profiles in Asthmatic Airways

Allergy, EarlyView.
Min‐Gyung Baek, Sangcheol Park, Young‐Chan Kim, Kyoung‐Hee Sohn, Jung Wook Kim, Kwang Jun Lee, Sang‐Heon Cho, Hye‐Ryun Kang, Hana Yi   +8 more
wiley   +1 more source

Geographic variation in the eukaryotic virome of human diarrhea

Virology, 2014
Little is known about the population of eukaryotic viruses in the human gut ("virome") or the potential role it may play in disease. We used a metagenomic approach to define and compare the eukaryotic viromes in pediatric diarrhea cohorts from two locations (Melbourne and Northern Territory, Australia).
Holtz, LR, Cao, S, Zhao, G, Bauer, IK, Denno, DM, Klein, EJ, Antonio, M, Stine, OC, Snelling, TL, Kirkwood, CD, Wang, D   +10 more
openaire   +5 more sources

The emerging role of the gut virome in necrotizing enterocolitis

Heliyon
Necrotizing enterocolitis (NEC) is the most common gastrointestinal emergency in neonates, particularly preterm infants. Many factors can lead to NEC, but microbial dysbiosis is one of the most important risk factors that can induce this disease.
Cong Yi, Jia Chen, Xiang She
doaj   +1 more source

Wastewater sequencing reveals community and variant dynamics of the collective human virome. [PDF]

Nat Commun, 2023
Tisza M, Javornik Cregeen S, Avadhanula V, Zhang P, Ayvaz T, Feliz K, Hoffman KL, Clark JR, Terwilliger A, Ross MC, Cormier J, Moreno H, Wang L, Payne K, Henke D, Troisi C, Wu F, Rios J, Deegan J, Hansen B, Balliew J, Gitter A, Zhang K, Li R, Bauer CX, Mena KD, Piedra PA, Petrosino JF, Boerwinkle E, Maresso AW.   +29 more
europepmc   +1 more source

Global genome analysis reveals a vast and dynamic anellovirus landscape within the human virome [PDF]

, 2021
Cesar Arze, Simeon Springer, Gytis Dudas, Sneha Patel, Agamoni Bhattacharyya, Harish Swaminathan, Carlo Brugnara, Simon Delagrave, Tuyen Ong, Avak Kahvejian, Yann Echelard, Erica G. Weinstein, Roger J. Hajjar, Kristian G. Andersen, Nathan L. Yozwiak   +14 more
openalex   +1 more source