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Metagenomics and the Human Virome in Asymptomatic Individuals
Annual Review of Microbiology, 2016High-throughput sequencing technologies have revolutionized how we think about viruses. Investigators can now go beyond pathogenic viruses and have access to the thousands of viruses that inhabit our bodies without causing clinical symptoms. By studying their interactions with each other, with other microbes, and with host genetics and immune systems,
Rascovan, Nicolas +2 more
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Progress and prospects of the healthy human gut virome
Current Opinion in Virology, 2021Not all viruses associated with humans cause disease. Non-pathogenic human-infecting viruses are predicted as important for immune system induction and preparation. Phages that infect bacteria are the most abundant predators of the human microbial ecosystem, promoting and maintaining bacterial diversity. Metagenomic analyses of the human gut virome and
Stephen R Stockdale, Colin Hill
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Giant oversights in the human gut virome
Gut, 2019We read with interest the paper by Zuo et al ,1 which used deep sequencing to identify gut mucosal virome alterations in individuals with UC. One of many interesting findings reported by the authors was the detection of giant viruses infecting algae and amoeba ( Mimivirus and Chrysochromulina ericina virus).
Thomas D S Sutton +2 more
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Translational Aspects of the Human Respiratory Virome
American Journal of Respiratory and Critical Care Medicine, 2016Despite the dominant role of community-acquired respiratory viruses as etiological agents of disease, there has been little focus to date on the translation of rapidly developing diagnostic modalities, such as next-generation sequencing techniques in the examination of lower respiratory tract samples.
Alicia B. Mitchell +2 more
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The Human Virome in Health and Disease
2016Early studies of the human microbiome were directed at bacteria. However, just as the bacterial microbiota affects human health and disease, viruses have analogous interactions. Thus, the human microbiome should be thought of as having a viral component, which is designated the human virome (Fig. 1 and Table 1).
Kristine M. Wylie, Gregory A. Storch
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Cervical cancer prevention and control in women living with human immunodeficiency virus
Ca-A Cancer Journal for Clinicians, 2021Philip E Castle, Vikrant V Sahasrabuddhe
exaly
Current treatment and recent progress in gastric cancer
Ca-A Cancer Journal for Clinicians, 2021Smita S Joshi, Brian D Badgwell
exaly
Metagenomic Analyses of the Human Gut Virome
2013The human gut harbors tens of trillions of microbes belonging to all three domains of life, Bacteria, Archaea, and Eukarya; most are members of Bacteria. These organisms collaborate and compete for functional niches and physical space: habitats), together forming a continuously functioning metabolic organ that influences many aspects of host biology ...
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