Results 61 to 70 of about 8,694 (213)

The blood DNA virome in 8,000 humans

PLOS Pathogens, 2017
The characterization of the blood virome is important for the safety of blood-derived transfusion products, and for the identification of emerging pathogens. We explored non-human sequence data from whole-genome sequencing of blood from 8,240 individuals, none of whom were ascertained for any infectious disease.
Ahmed Moustafa, Chao Xie, Ewen Kirkness, William Biggs, Emily Wong, Yaron Turpaz, Kenneth Bloom, Eric Delwart, Karen E. Nelson, J. Craig Venter, Amalio Telenti   +10 more
openaire   +4 more sources

The gut virome: the ‘missing link’ between gut bacteria and host immunity?

Therapeutic Advances in Gastroenterology, 2019
The human gut virome includes a diverse collection of viruses that infect our own cells as well as other commensal organisms, directly impacting on our well-being. Despite its predominance, the virome remains one of the least understood components of the
Indrani Mukhopadhya, Jonathan P. Segal, Simon R. Carding, Ailsa L. Hart, Georgina L. Hold   +4 more
doaj   +1 more source

Choice of assembly software has a critical impact on virome characterisation

Microbiome, 2019
Background The viral component of microbial communities plays a vital role in driving bacterial diversity, facilitating nutrient turnover and shaping community composition.
Thomas D. S. Sutton, Adam G. Clooney, Feargal J. Ryan, R. Paul Ross, Colin Hill   +4 more
doaj   +1 more source

Defense Systems and Prophage Detection in Streptococcus mutans Strains

Molecular Oral Microbiology, EarlyView.
ABSTRACT Although the species is extensively studied, limited data are available on antiphage defense systems (APDSs) in Streptococcus mutans. The present study aimed to explore the diversity and the occurrence of APDSs and to search for prophages in the genomes of clinical isolates of S. mutans using bioinformatics tools.
Olivier Claisse, Cas Mosterd, Claire Le Marrec, Johan Samot   +3 more
wiley   +1 more source

The Gut Virome Database Reveals Age-Dependent Patterns of Virome Diversity in the Human Gut [PDF]

Cell Host & Microbe, 2020
The gut microbiome profoundly affects human health and disease, and their infecting viruses are likely as important, but often missed because of reference database limitations. Here, we (1) built a human Gut Virome Database (GVD) from 2,697 viral particle or microbial metagenomes from 1,986 individuals representing 16 countries, (2) assess its ...
Gregory, Ann C., Zablocki, Olivier, Zayed, Ahmed A., Howell, Allison, Bolduc, Benjamin, Sullivan, Matthew B.   +5 more
openaire   +2 more sources

A blood safety perspective on emerging arboviral infections in the United Kingdom

Transfusion Medicine, EarlyView.
Abstract A core focus of the blood services is to maintain the blood supply whilst simultaneously being vigilant for potential threats to blood safety. At present, West Nile virus (WNV), Usutu virus (USUV), Dengue virus (DENV) and Tick‐borne encephalitis virus (TBEV) are considered primary arboviral threats to blood safety in the UK and Northern Europe.
Piya Rajendra, Shannah Secret, Su Brailsford, Tanya Golubchik, Peter Simmonds, Heli Harvala   +5 more
wiley   +1 more source

Molecular Characterization and Epidemiology of Human Noroviruses in the Sverdlovsk Region, Russian Federation

Viruses
Human noroviruses (HuNoVs) stand as the primary cause of acute viral gastroenteritis outbreaks worldwide, particularly impacting children under the age of five.
Roman Bykov, Tarek Itani, Daria Pletenchuk, Olesia Ohlopkova, Alexey Moshkin, Marina Stepanyuk, Aleksandr Semenov   +6 more
doaj   +1 more source

Microbial‐Immune Interplay in CNS Autoimmune Diseases: Lessons from Animal Models and Clinical Studies

European Journal of Immunology, Volume 56, Issue 2, February 2026.
Mechanism of action of the intestinal microbiota on CNS autoimmune diseases. Environmental factors shape gut microbiota composition; dysbiosis alters microbial metabolites and antigenic signals. These modulate innate and adaptive immunity, affect barrier integrity, and influence CNS‐resident cells such as microglia and astrocytes, contributing to ...
Matteo Ceccon, Francesca Ronchi
wiley   +1 more source

Plasma virome dynamics in chronic hepatitis B virus infected patients

Frontiers in Microbiology, 2023
The virome remains an understudied domain of the human microbiome. The role of commensal viruses on the outcome of infections with known pathogens is not well characterized.
Marijn Thijssen, Frank Tacke, Lore Van Espen, David Cassiman, Mahmoud Naser Aldine, Frederik Nevens, Marc Van Ranst, Jelle Matthijnssens, Mahmoud Reza Pourkarim, Mahmoud Reza Pourkarim, Mahmoud Reza Pourkarim   +10 more
doaj   +1 more source

Harnessing viral footprints in circulating free DNA (cfDNA) for early cancer detection: A focus on liquid‐biopsy‐based screening

International Journal of Cancer, Volume 158, Issue 3, Page 511-526, 1 February 2026.
Abstract Viral infections play a significant role in cancer development, making detecting viral signatures a promising approach for early cancer diagnosis. Circulating free DNA (cfDNA), released into the bloodstream by tumors and other cells, has emerged as a powerful biomarker for non‐invasive cancer screening.
Richard Donkor Amponsah, Emmanuel Addai Gyabaah, Moro Amidu, Zhao Cheng, Fazlur Rahman Talukdar   +4 more
wiley   +1 more source