Results 81 to 90 of about 8,242 (199)

High‐throughput generic single‐entity sequencing using droplet microfluidics

open access: yesiMeta, EarlyView.
We present Generic Single Entity Sequencing (GSE‐Seq), a droplet‐based workflow that generates monoclonal barcodes by one‐step PCR, performs dissolvable hydrogel‐enabled reactions for genome processing, and attaches barcodes during in‐droplet library preparation. Barcoded fragments are pooled and sequenced with PacBio long‐read sequencing. Barcodes are
Guoping Wang   +14 more
wiley   +1 more source

Dysbiosis in Peripheral Blood Mononuclear Cell Virome Associated With Systemic Lupus Erythematosus

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
Objective: Pathogen infection plays a role in the development and progression of systemic lupus erythematosus (SLE). Previous studies showed that peripheral blood mononuclear cells (PBMCs) harbor many viral communities. However, little is known about the
Gangqiang Guo   +13 more
doaj   +1 more source

The Emerging Role of the Gut Virome in Health and Inflammatory Bowel Disease: Challenges, Covariates and a Viral Imbalance

open access: yesViruses, 2023
Virome research is a rapidly growing area in the microbiome field that is increasingly associated with human diseases, such as inflammatory bowel disease (IBD).
Daan Jansen, Jelle Matthijnssens
doaj   +1 more source

The Revival of the Battle between David and Goliath in the Enteric Viruses and Microbiota Struggle: Potential Implication for Celiac Disease

open access: yesMicroorganisms, 2019
The human gut is inhabited by overcrowded prokaryotic communities, a major component of which is the virome, comprised of viruses, bacteriophages, archaea, eukaryotes and bacteria.
Aaron Lerner   +2 more
doaj   +1 more source

Evidence for a Role of Extraintestinal Pathogenic Escherichia coli, Enterococcus faecalis and Streptococcus gallolyticus in the Aetiology of Exudative Cloacitis in the Critically Endangered Kākāpō (Strigops habroptilus)

open access: yesMolecular Ecology, EarlyView.
ABSTRACT The kākāpō is a critically endangered flightless parrot which suffers from exudative cloacitis, a debilitating disease resulting in inflammation of the vent margin or cloaca. Despite this disease emerging over 20 years ago, the cause of exudative cloacitis remains elusive.
Rebecca K. French   +13 more
wiley   +1 more source

The Virome of the Human Respiratory Tract

open access: yesClinics in Chest Medicine, 2017
The human respiratory tract virome is defined here as the viruses present in the human respiratory tract that can infect human cells. Sensitive, culture-independent molecular assays (polymerase chain reaction and high-throughput sequencing) reveal that in addition to common viruses that cause acute, symptomatic infections the virome also includes ...
openaire   +3 more sources

Bumble Bees and Honey Bees on Islands Harbour Reduced Viral Species Richness, Yet Honey Bee Populations Are Dominated by a Deformed Wing Virus Recombinant

open access: yesMolecular Ecology, EarlyView.
ABSTRACT Pollinators harbour diverse RNA viromes that play a vital role in their health. Yet, factors that shape viral communities are often unclear. The European honey bee (Apis mellifera) is experiencing a viral epidemic since the emergence of the parasitic mite Varroa destructor (varroa) introduced vector‐borne transmission, which has also been ...
Jana Dobelmann, Lena Wilfert
wiley   +1 more source

A metagenomic catalog of the early-life human gut virome

open access: yesNature Communications
Early-life human gut microbiome is a pivotal driver of gut homeostasis and infant health. However, the viral component (known as “virome”) remains mostly unexplored.
Shuqin Zeng   +11 more
doaj   +1 more source

Variations of the Virome in Raw and Treated Water: A One‐Year Follow‐Up at Six Different Drinking Water Treatment Plants

open access: yesEnvironmental Microbiology Reports, Volume 17, Issue 6, December 2025.
This paper describes monitoring of outgoing water from drinking water treatment plants, geographically spread over half of Sweden and sampled every other month for 1 year. We found differences in the virome from the different water sources from each plant as well as differences in virus size and seasonal variation, where we also could detect viruses in
Fredy Saguti   +10 more
wiley   +1 more source

TTV Species Diversity as a Novel Biomarker of Immune Dysregulation in Aging

open access: yesJournal of Medical Virology, Volume 97, Issue 11, November 2025.
ABSTRACT Torquetenovirus (TTV) is a prevalent virus whose clinical significance remains unclear, potentially linked to immunosenescence. This study examines TTV species in relation to immune impairment, inflammation, and cellular stress response in aging.
Federica Novazzi   +35 more
wiley   +1 more source

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