Results 121 to 130 of about 5,101,776 (315)

Corrigendum: Examining human-animal interactions and their effect on multidimensional frailty in later life: a scoping review

Frontiers in Public Health, 2023
Ashley Taeckens, Mary Corcoran, Kaipeng Wang, Kevin N. Morris   +3 more
doaj   +1 more source

Mitigating poverty to attain SDG 1 (No poverty) in South Africa: Experiences of social relief of distress grant beneficiaries

International Review of Social Sciences Research
South Africa is recognised across the globe for its developmental social welfare programs and progressive social security benefits. However, the COVID-19 pandemic revealed significant shortcomings in the government’s social welfare response to vulnerable
Khuthadzo Mbedzi , Emmison Muleya
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Human Resource Management at Work: The Definitive Guide

, 2020
A leading textbook in its field, Human Resource Management at Work is a comprehensive guide to the theory and practice of HRM. Aligned to the CIPD Level 7 qualification yet also relevant on non-CIPD accredited HR masters courses, this book covers ...
Kynighou, Anastasia, Marchington, Mick, Wilkinson, Adrian, Donnelly, Rory   +3 more
core  

Inner Working of the Human Body

HCA Healthcare Journal of Medicine
Description This evocative artwork is inspired by the inner workings of the human body, specifically the complexities of blood flow and vascular systems. The deep reds and dynamic patterns represent the movement of blood through arteries and veins, while the interplay of lighter hues evokes the diffusion of oxygen and nutrients.
openaire   +2 more sources

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Factors Motivating Black Female Learners to Enroll in STEM Streams and Their Strategies to Cope with the Curriculum: A Qualitative Inquiry in a South African Secondary School

Education Sciences
Participation in science, technology, engineering, and mathematics (STEM) fields is crucial, as these fields present an opportunity for individuals to overcome socio-economic adversities such as unemployment and poverty.
Hope Nosipho Sikhosana, Hlologelo Malatji, Aldridge Tafadzwa Munyoro, Thobeka Sweetness Nkomo   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

The importance of social skills for the future of work [PDF]

, 2016
Technological change and precarity has made social skills increasingly important in the workplace for both permanent and non-permanent staff throughout the labour market. This is especially true for those in precarious work located in the growing service
Steele, Zanian, Piercy, Gemma Louise
core  

Trauma context exerts intergenerational effects on child mental health via DNA methylation

Epigenetics
Many people experience traumatic or negative events, but few develop mental health issues as a result. This study investigated whether newborn DNA methylation (DNAm) previously associated with maternal childhood physical abuse by her father affected the ...
Stefanie Pilkay, Andie Riffer, Andrew Carroll   +2 more
doaj   +1 more source