Results 61 to 70 of about 5,101,776 (315)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

THE LIFE EXPERIENCES OF ADOLESCENT SEXUAL OFFENDERS: FACTORS THAT CONTRIBUTE TO OFFENDING BEHAVIOURS

Social Work/Maatskaplike Werk, 2014
This study, based on the case studies of 25 adolescent sex offenders, was designed to understand those factors that contribute to adolescent sexual offending.
Linda Naidoo, Vishanthie Sewpaul
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Measuring the One Health impacts associated with creating access to veterinary care before and during the COVID-19 pandemic

Frontiers in Public Health
Integrating community perceptions into One Health assessments is critical to understanding the structural barriers that create disproportionate health outcomes for community members, their pets, and the ecosystems that encompass them, particularly in ...
Sloane M. Hawes, Kaleigh M. O’Reilly, Tess M. Mascitelli, Jordan Winczewski, Romi Dazzio, Amanda Arrington, Kevin N. Morris   +6 more
doaj   +1 more source

THE CAPACITY OF A HUMAN MUSCLE FOR WORK. [PDF]

Journal of the American Medical Association, 1903
15 p. :
openaire   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Work Incentives Network (WIN). Arabic

, 2023
"100-295302 ODHS 9889 (08/23) Arabic."This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.

core  

Social workers’ motivation to provide effective service in a challenging environment of illegal substance abuse

Health SA Gesondheid: Journal of Interdisciplinary Health Sciences
Background: The social work profession is portrayed as a stressful occupation that brings about depression and demoralisation upon social workers. It is believed that working towards changing an individual, group or community at large is difficult.
Oratile Khampepe, Nathaniel P. Kgadima
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Work Incentives Network (WIN). Vietnamese

, 2023
"100-295302 ODHS 9889 (8/23) Vietnamese."This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.

core