Artificial intelligence (AI) psychosis: mechanisms, clinical risks and safety considerations in generative AI chatbots. [PDF]
Olisaeloka L, Nunez JJ, Vigo DV, Ng R.
europepmc +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Examining the influence of the domestic social robot anthropomorphism on users' perceived affinity via intelligent design process: robot social presence as a mediator. [PDF]
Chen T, Cui T, Zhang Y, Xu Z, Jia Y.
europepmc +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Exploring Non-Embodied AI-Based Digital Companions for Older Adults in Aging and Care Contexts: Protocol for a Scoping Review. [PDF]
Hung L, Chiu YT, Ghodsi M.
europepmc +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
The Technologically Mediated Motherhood Constellation: Smartphone and AI as Novel Actors in Maternal Psychic Organization. [PDF]
Cerniglia L, Cimino S.
europepmc +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
This paper provides a pragmatic argument on how best interaction designers and researchers can influence and perhaps even guide the interaction design process of the ever accelerating digital revolution.
Bonner, John V.H.
core
What ethical AI and robots could mean: a conceptual and ethical reflection. [PDF]
Sedlakova J.
europepmc +1 more source

