Results 31 to 40 of about 945,118 (264)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Operators and their human–robot interdependencies: implications of distinct job decision latitudes for sustainable work and high performance

Frontiers in Robotics and AI
The collaborative robot (cobot) has the potential to remove barriers for individual operators when deciding on the deployment of robotics in their work.
Milan R. Wolffgramm, Milan R. Wolffgramm, Milan R. Wolffgramm, Stephan Corporaal, Stephan Corporaal, Aard J. Groen   +5 more
doaj   +1 more source

Exploring Human-Data Interaction in Clinical Decision-making Using Scenarios: Co-design Study

JMIR Human Factors, 2022
BackgroundWhen caring for patients with chronic conditions such as chronic obstructive pulmonary disease (COPD), health care professionals (HCPs) rely on multiple data sources to make decisions.
Helena Tendedez, Maria-Angela Ferrario, Roisin McNaney, Adrian Gradinar   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Patterns of Cooperative Interaction: Linking Ethnomethodology and Design

, 2004
© ACM, 2004. This is the author's version of the work. It is posted here by permission of ACM for your personal use. Not for redistribution. The definitive version was published in ACM Transactions on Computer-Human Interaction, 11(1): 59-89, 10730516 ...
Sommerville, I., Martin, D., Ian Sommerville, David Martin, Sommerville, Ian   +4 more
core   +1 more source

Sharing Stress With a Robot: What Would a Robot Say?

Human-Machine Communication Journal, 2020
With the prevalence of mental health problems today, designing human-robot interaction for mental health intervention is not only possible, but critical.
Honson Y. Ling, Elin A. Björling
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Human Work Interaction Design (HWID): Design for Challenging Work Environments

, 2015
This one-day workshop aims to contribute to the goals of the IFIP 13.6 Human Work Interaction Design (HWID) working group, i.e., to establish relationships between empirical work-domain studies and recent developments in interaction design.
Campos, Pedro, Gonçalves, Frederica, V. Fuchsberger, Barricelli, Barbara, Rita, Pedro Campos, B.R. Barricelli, F. Gonçalves, Frederica Gonçalves, Barricelli, Barbara Rita, M. Murer, J. Abdelnour Nocera, Verena Fuchsberger, Manfred Tscheligi, M. Tscheligi, J. Abdelnour-Nocera, Murer, Martin, Martin Murer, P. Campos, José Abdelnour-Nocera, Barbara Rita Barricelli, Abdelnour-Nocera, José, Tscheligi, Manfred, Fuchsberger, Verena   +22 more
core   +1 more source

Design of a videogame to explore morality [PDF]

, 2016
A number of video games involve moral narratives or require the player to make moral decisions and research from psychologists has helped to understand the effects video game content can have on how individuals behave.
Hodge, Sarah E., Sarah K Hodge, Jacqui Taylor, Taylor-Jackson, Jacqui (R19920), McAlaney, John, Christos Gatzidis, John McAlaney, Gatzidis, Christos   +7 more
core   +1 more source

Designing Human-Centred Adaptive AI Navigation for Blind and Visually Impaired Individuals: A Cognitive Load-Aware Framework for Accessible Urban Mobility

AI
Artificial intelligence systems increasingly mediate high-stakes human activities, yet urban navigation remains highly challenging for blind and visually impaired individuals.
Pilar Herrero-Martín, Álvaro García-Ballestero   +1 more
doaj   +1 more source