Results 81 to 90 of about 281,579 (301)

Beyond gender mainstreaming: transforming humanitarian action, organizations and culture. [PDF]

J Int Humanit Action, 2023
Gupta GR, Grown C, Fewer S, Gupta R, Nowrojee S.   +4 more
europepmc   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Humanitarianism and the Sendai Framework: A 10-Year Review of Converging and Diverging Paths

International Journal of Disaster Risk Science
Humanitarian action and disaster risk reduction are essential in addressing global vulnerability to disasters and crises. The Sendai Framework for Disaster Risk Reduction 2015–2030 (SFDRR), adopted in 2015, has garnered significant attention for its role
Rodrigo Mena
doaj   +1 more source

Natural language processing for humanitarian action: Opportunities, challenges, and the path toward humanitarian NLP. [PDF]

Front Big Data, 2023
Rocca R, Tamagnone N, Fekih S, Contla X, Rekabsaz N.   +4 more
europepmc   +1 more source

Questionable Accountability: MSF and Sphere in 2003. [PDF]

, 2004
This article examines the relationship between Médecins Sans Frontières (MSF) and the Sphere Project. Prior to revisiting the concerns MSF had with the project, it looks at factors that give rise to differences between NGOs and cites some reasons for why
Bouchet-Saulnier, Brabant, Braughman, Buchanan-Smith, Darcy, Fox, Griekspoor, Grien, Mompoint, Perrin, Ridley, Salama, Slim, Stoddard, Terry, Terry   +15 more
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Rethinking democracy in global network governance: norm polysemy, pluralism, and agonistic engagement

International Theory
This article examines the democratic potential of global network governance. It critiques conventional legitimacy frameworks that focus on the institutional qualities of governance networks for evading deeper ethical questions about how to deal with ...
Kilian Spandler
doaj   +1 more source

Measuring results of humanitarian action: adapting public health indicators to different contexts. [PDF]

Confl Health, 2022
Altare C, Weiss W, Ramadan M, Tappis H, Spiegel PB.   +4 more
europepmc   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Humanitarian action in academic institutions: a case study in the ethical stewardship of unidentified forensic cases. [PDF]

Forensic Sci Res, 2022
Goldstein JZ, Moe ME, Wiedenmeyer EL, Banks PM, Mavroudas SR, Hamilton MD.   +5 more
europepmc   +1 more source