Results 151 to 160 of about 15,276 (261)

A descriptive analysis of a medical humanitarian aid initiative for quality perinatal management in war-torn Ukraine. [PDF]

Confl Health
Mogilevkina I, Dobryanskyy D, MacDonald R, Watson D, Southall D.   +4 more
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Leptospirosis Risk Assessment in Rodent Populations and Environmental Reservoirs in Humanitarian Aid Settings in Thailand. [PDF]

Microorganisms
Krairojananan P, Wasuworawong K, Leepitakrat S, Monkanna T, Wanja EW, Davidson SA, Poole-Smith BK, McCardle PW, Mann A, Lindroth EJ.   +9 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The impact of humanitarian aid on financial toxicity among cancer patients in Northwest Syria. [PDF]

BMC Health Serv Res
Al-Abdulla O, Sonsuz AA, Alaref M, Albakor B, Kauhanen J.   +4 more
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Correction: Impact of Ebola and COVID‑19 on maternal, neonatal, and child health care among populations affected by conflicts: a scoping review exploring demand and supply‑side barriers and solutions

Conflict and Health
Yasir Shafiq, Elena Rubini, Zoha Zahid Fazal, Muhammad Murtaza Bukhari, Maheen Zakaria, Noor ul Huda Zeeshan, Ameer Muhammad, Luca Ragazzoni, Francesco Barone‑Adesi, Martina Valente   +9 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Advancing Global Health Equity: Saudi Arabia’s Leadership in Conjoined Twins Care and Humanitarian Outreach

Journal of Epidemiology and Global Health
Abdullah A. Al Rabeeah, Ziad A. Memish
doaj   +1 more source

The occurrence of and factors associated with mental ill-health amongst humanitarian aid workers: A systematic review and meta-analysis. [PDF]

PLoS One
Cameron L, McCauley M, van den Broek N, McCauley H.   +3 more
europepmc   +1 more source