Results 21 to 30 of about 1,927,609 (247)
Advanced Science, EarlyView.We report a new thiolate‐reactive α,α‐gem‐dibromo lactam warhead that activates transcription factor Nrf2 and demonstrates anti‐inflammatory activities, which have implications in cancer, neurodegeneration, and cardiovascular diseases. RNA‐seq illuminated detailed transcriptional profiles, and chemical reactions with cysteine‐containing compounds ...
Beau R. Brummel +16 more
wiley +1 more source
Advanced Science, EarlyView.Cytoplasmic aggregation of TDP‐43 is a common pathological feature in amyotrophic lateral sclerosis, frontotemporal lobar degeneration, and Alzheimer's disease with TDP‐43 pathology. This study reports that wild‐type PDI slows down phase separation of TDP‐43 through direct interaction with TDP‐43.
Jia‐Qi Liu +14 more
wiley +1 more source
, 2009 · This article describes an initiative designed to engage a broad cross section of Californians in the humanities. Initial findings from book reading groups were that participants were predominantly white, middle-aged women.
Mudge, Alden +3 more
core +1 more source
Personalized Network‐Guided Neuromodulation Enhances Human Working Memory
Advanced Science, EarlyView.A personalized neuromodulation framework combining individualized functional brain network targeting with real‐time neural decoding is introduced. Using concurrent TMS–fMRI, participant‐specific stimulation targets and optimal frequencies are identified. Only optimal‐frequency stimulation improves working memory across sessions.
Ahsan Khan +13 more
wiley +1 more source
Big? Smart? Clean? Messy? Data in the Humanities [PDF]
, 2013 This paper is about data in the humanities. Most of my colleagues in literary and cultural studies would not necessarily speak of their objects of study as “data.” If you ask them what it is they are studying, they would rather speak of books, paintings ...
Schöch, Christof, Christof Schöch
core +1 more source
Mechanistic Understanding of Protein–MOF Integration Through Surfactant‐Driven Interfacial Design
Advanced Science, EarlyView.This study reveals how surfactant‐driven interfacial design governs the assembly and stability of protein@MOF composites. Using lipid‐based nonionic surfactants, we modulate protein–MOF interactions to improve encapsulation efficiency, MOF crystallization, and catalytic performance.
Ehsan Rashidniyaghi +4 more
wiley +1 more source
Inspiring Desire: A new materialist bent to doctoral education in Arts and Humanities
, 2017 Doctoral learning entails transition from experienced student to stance defending researcher, exposed to international critique: a disorientation and reorientation into a new identity. Arts and Humanities candidates typically navigate these moves without
Gunn, V +4 more
core +1 more source
Agribusiness, EarlyView.ABSTRACT Farmers markets provide a direct‐to‐consumer marketing path for farmers and small businesses, facilitating customer discovery and product refinement. This paper explores farmers markets as a business incubator, with a focus on beginning vendors and resilience to a shock, namely, COVID‐19 market restrictions.
Mallory L. Rahe +2 more
wiley +1 more source
An examination of the physical and the digital qualities of humanities research
, 2008 Traditionally humanities scholars have worked in physical environments and with physical artefacts. Libraries are familiar places, built on cultural traditions over thousands of years, and books are comfortable research companions.
Rimmer, J +9 more
core +1 more source
Advanced Intelligent Discovery, EarlyView.This study applies QSAR‐based new approach methodologies to 90 synthetic tattoo and permanent makeup pigments, revealing systemic links between their physicochemical properties and absorption, distribution, metabolism, and elimination profiles. The correlation‐driven analysis using SwissADME, ChemBCPP, and principal component analysis uncovers insights
Girija Bansod +10 more
wiley +1 more source