Results 161 to 170 of about 1,288,714 (407)
Advancement of Global Peace Building from the Periscope of Kant’s Philosophy of Perpetual Peace [PDF]
, 2019 The topic of discourse titled “Advancement of Global Peace Building from the Periscope of Kant‟s Philosophy of Perpetual Peace” is centered on the clarion call for the placement of the study of Arts and Humanities at the forefront of human existential ...
Eyo, Emmanuel Bassey
core
Molecular Oncology, EarlyView.We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić +31 more
wiley +1 more source
A Check List of Canadian Literature and Background Materials, 1628–1950. Compiled by <italic>Reginald Eyre Watters</italic> for the Humanities Research Council of Canada. (Toronto: University of Toronto Press. 1959. Pp. xx, 789. $15.00.) and Bibliography of Canadian Bibliographies. Compiled under the direction of <italic>Raymond Tanghe</italic>. (Toronto: University of Toronto Press in association with the Bibliographical Society of Canada. 196o. Pp. 206. $10.00.) [PDF]
, 1961 John Hall Stewart
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Hijacking the BAF complex: the mechanistic interplay of ARID1A and EWS::FLI1 in Ewing sarcoma
Molecular Oncology, EarlyView.Ewing sarcoma is driven by the EWS::FLI1 fusion protein, which disrupts gene expression by hijacking the BAF complex via ARID1A. ARID1A's ability to form biomolecular condensates is crucial for tumor growth, making it a potential therapeutic target. However, targeting these transient condensates is challenging, requiring further research. Ewing sarcoma,
Erich J. Sohn, David S. Libich
wiley +1 more source
Genomic landscape and preclinical models of angiosarcoma
Molecular Oncology, EarlyView.Angiosarcomas are a rare and aggressive cancer with a poor prognosis for patients. The genomic landscape of angiosarcoma can be highly complex and heterogenous; however, recent studies have identified some common features especially within anatomic and molecular subgroups.
Annaleigh Benton +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale +9 more
wiley +1 more source
Molecular Oncology, EarlyView.The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu +3 more
wiley +1 more source