Handbook of Latin American Studies, No. 36: Humanities [PDF]
Ione Stuessy Wright
openalex +1 more source
Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas+15 more
wiley +1 more source
Liber Apologeticus de Omni Statu Humanae Naturae. A Defence of Human Nature in Every State (c. 1460) A Moral Play by Thomas Chaundler. Edited from Manuscript with English Translation, Introduction, and Notes by Doris Enright-Clark Shoukri. The Modern Humanities Research Association in conjunction with Renaissance Society of America London and New York. 1974, X - 208 pp. with 17 full page illustration. £ 12, or $ 36 [PDF]
Germain Marc’hadour
openalex +1 more source
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien+7 more
wiley +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park+6 more
wiley +1 more source
A Scoping Review of Programs of Active Arts Engagement in International Medical Curricula. [PDF]
Moula Z+7 more
europepmc +1 more source
Archaeology in the Digital Age: From Paper to Databases
Research units in archaeology often manage large and precious archives containing various documents, including reports on fieldwork, scholarly studies and reference books.
Ferguth, Johan+3 more
core
Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren+4 more
wiley +1 more source
A national perspective: integrating medical humanities to address burnout and stress in Chinese medical education. [PDF]
Zhai H+8 more
europepmc +1 more source
Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song+13 more
wiley +1 more source