Results 21 to 30 of about 84,220 (268)

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro, Freda Qi, Karen Colwill, Alina D. Dorogy, Ying Liu, Michelle Science, Anne‐Claude Gingras, James M. Rini, Sumit Gupta, Sarah Alexander, Shelly Bolotin, Tania H. Watts   +11 more
wiley   +1 more source

A randomized controlled study on the clinical application of ‘Flying Needle’ painless phlebotomy technology

Scientific Reports
Venipuncture-related pain and needle fear can reduce patient cooperation and worsen the phlebotomy experience. This study was a comparative study conducted on 600 outpatients of Xiamen Humanity Hospital from September to December 2022, aiming to explore ...
Rongfang Zhang, Yuning Lin, Songping Chen, Kaili Zhang, Peijie Xu, Xiaomei Feng, Fanglin Liu, Xinyi Zhi, Zhongying Zhang   +8 more
doaj   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

The safety, tolerability, pharmacokinetics, and pharmacodynamics of nebulized pegylated interferon α-2b in healthy adults: a randomized phase 1 trial

BMC Pharmacology and Toxicology
Background Interferons (IFNs) are proteins that combat viruses and regulate the immune system. Studies have demonstrated that aerosol inhalation of IFNα is both effective and safe for treating respiratory infections.
Wenqi Huang, Yanneng Kang, Yajun Zhao, Jiao Yang, Changjuan Dai, Weibing Wu, Jinchao Xu, Wen Jin, Xiaolu Wu, Qing Zhou   +9 more
doaj   +1 more source

Research Progress on perinatal E. coli infection

Frontiers in Microbiology
Against the backdrop of widespread implementation of intrapartum prophylaxis for group B streptococcus (GBS), E. coli has emerged as a major pathogen of early-onset neonatal sepsis (EOS) and neonatal meningitis.
Yuning Lin, Wenzhen Zhao, Hongyan Xie, Zhenyi Lv, Songping Chen, Hongwei Jin, Jianning Wu   +6 more
doaj   +1 more source

Nourishing social solidarity in exchanging gifts: a study on social exchange in Shanghai communities during COVID-19 lockdown

Humanities & Social Sciences Communications, 2023
During the COVID-19 lockdown in Shanghai, we found many social exchanges within communities. In this study, we focus on exploring the driving forces behind social exchanges and their impacts on the social solidarity of local communities.
Youjia Zhou, Chen Dong
doaj   +1 more source

Learning Representations by Humans, for Humans

, 2019
We propose a new, complementary approach to interpretability, in which machines are not considered as experts whose role it is to suggest what should be done and why, but rather as advisers. The objective of these models is to communicate to a human decision-maker not what to decide but how to decide.
Sophie Hilgard, Nir Rosenfeld, Mahzarin R. Banaji, Jack Cao, David Parkes   +4 more
openaire   +5 more sources

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source

“They won’t prosecute, but they will though:” the continuing struggle between criminalization and harm reduction within the criminal justice system in the context of an opioid overdose crisis

Harm Reduction Journal
People who use drugs (PWUD) come into frequent contact with the police including after calling for emergency medical services when witnessing an opioid overdose.
Julia Dickson-Gomez, Sarah Krechel, Jessica Ohlrich, Jennifer Hernandez-Meier, Constance Kostelac   +4 more
doaj   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source