Results 241 to 250 of about 95,544 (345)

Framework humanization enhances GM3(Neu5Gc)-targeting CAR-T cell function by reducing tonic signaling. [PDF]

Front Immunol
Tu J, Li X, Zhu Y, Li S, Zhang G, He Y, Zhang C, Lu Z.   +7 more
europepmc   +1 more source

HUMANIZATION VISIT FAMILY IN AN ADULT ICU SOUTHEAST OF MATO GROSSO

, 2012
Vagner Nascimento
openalex   +1 more source

Clinical trial of safety and antitumor activity of farletuzumab ecteribulin in patients with platinum‐resistant ovarian cancer: Phase I expansion results

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective In the dose‐escalation part of Study 101, which included multiple tumor types, objective responses were observed in 10 of 22 patients across multiple dose levels of farletuzumab ecteribulin (FZEC). We explored the safety/antitumor activity of FZEC in patients with platinum‐resistant ovarian cancer (PROC) from the Study 101 expansion ...
Kan Yonemori, Mayu Yunokawa, Koji Matsumoto, Kazuhiro Takehara, Kosei Hasegawa, Yasuyuki Hirashima, Hidenori Kato, Hiroki Ikezawa, Yohei Otake, Wataru Yusa, Takuma Miura, Shin Nishio   +11 more
wiley   +1 more source

Enhanced humoral and HLA‐A2‐restricted dengue virus‐specific T‐cell responses in humanized BLT NSG mice

, 2012
Smita Jaiswal, Pamela Pazoles, Marcia Woda, Leonard D. Shultz, Dale L. Greiner, Michael A. Brehm, Anuja Mathew   +6 more
openalex   +2 more sources

Targeting DGKα/PA axis inhibits tumor immune evasion and augments sensitivity to immunotherapy in gastrointestinal cancers

iMeta, EarlyView.
Immune checkpoint inhibitors (ICIs) have shown promising antitumor efficacy in certain types of solid tumors. However, the efficacy of ICIs remains unsatisfactory owing to the dysregulation of signaling pathways in local tumor tissues. Here, we reveal that diacylglycerol kinase α (DGKα)‐derived phosphatidic acid (PA) directly binds to nuclear factor‐κB
Jie Chen, Siqi Liu, Ting Peng, Fenglong Wang, Yuheng Zhu, Jingyuan Pang, Qingnan Wu, Yan Wang, Qimin Zhan   +8 more
wiley   +1 more source

The effects of human training data (HTD) explanation on purchase intention for artificial intelligence (AI) technologies. [PDF]

PLoS One
Dharmaputri SK, Nyilasy G, Nagpal A, Lei J.   +3 more
europepmc   +1 more source

Digital Humanities? E-Humanities? Social Humanities?

Krosworldia, 2013
openaire   +2 more sources

Respiratory Syncytial Virus Under the Lens of Structure: From Prefusion Stabilization to Next‐Generation Immunotherapies

iNew Medicine, EarlyView.
This illustration integrates key concepts covered in the review, including high‐risk populations, viral structure, host entry factors, the replication cycle, and licensed antibody‐based prevention strategies. ABSTRACT Respiratory syncytial virus (RSV) is a negative‐sense RNA virus belonging to the genus Orthopneumovirus within the family Pneumoviridae.
Zekai Cheng, Qianqian Wang, Jiachen Zhang, Sandra Chiu   +3 more
wiley   +1 more source

Empathy-Driven Humanization: Employment Instability, Burnout, and Work Engagement Among Temporary Nurses in a Sustainable Workforce Model. [PDF]

Nurs Rep
Prieto-de Benito S, Ruíz-Núñez C, Hervás-Pérez JP, Ruíz-Zaldibar C, López-Espuela F, Caballero de la Calle R, Herrera-Peco I.   +6 more
europepmc   +1 more source

Gut microbiome‐derived metabolites show promise in cancer research and therapy

Interdisciplinary Medicine, EarlyView.
The metabolites produced by the gut microbiome, which are subject to regulation by multiple factors, play a pivotal role in the progression of various types of cancer. These metabolites not only function as potential biomarkers for the early detection and monitoring of tumor development, but also actively participate in cancer therapeutic processes ...
Kangjie Yang, Yifan Wang, Daolin Tang, Peilong Li, Lutao Du   +4 more
wiley   +1 more source