Results 241 to 250 of about 61,570 (310)

Comment on "Perception of fertility, quality of life, and depression in women undergoing assisted reproductive treatment". [PDF]

JBRA Assist Reprod
Kumar S.
europepmc   +1 more source

Potent monoclonal antibodies against multidrug‐resistant hypervirulent Klebsiella pneumoniae

Interdisciplinary Medicine, EarlyView.
A novel immunization strategy using a low‐virulence, multidrug‐resistant strain yields synergistic monoclonal antibodies against hypervirulent Klebsiella pneumoniae. These antibodies provide cross‐serotype protection through a dual‐mechanism of pathogen clearance and immunomodulation, offering a promising non‐antibiotic therapeutic for resistant ...
Yushan Jiang, Zhuolin Li, Yang Yang, Zihan He, Tyuji Hoshino, Vladislav Victorovich Khrustalev, Qing Zhu, Weiling Wu, Wei Zhao, Chenguang Shen, Shi Ouyang   +10 more
wiley   +1 more source

GB20-5A8-31, an anti-TL1A antibody for treating inflammatory bowel disease. [PDF]

Front Immunol
Huang Y, You Q, Yao T, Tong Y, Yang X, Zhang X, Huang X, Chen Q, Lu F, Li H, Wang J, Qin S.   +11 more
europepmc   +1 more source

SUMOylation regulates tumorigenesis and progression: Molecular mechanisms and therapeutic applications

Interdisciplinary Medicine, EarlyView.
SUMOylation, a dynamic post‐translational modification, acts as a master regulator at the heart of tumor malignancy. Our work delineates how the SUMOylation cycle—mediated by E1/E2/E3 enzymes and reversed by SENPs—orchestrates multiple hallmarks of cancer. The central pathway converges on three critical pathological axes: 1.
Yimao Wu, Zichang Chen, Yinting Hu, Gokhan Zengin, Qian Zhang, Meng‐Yao Li, Wenlong Sun   +6 more
wiley   +1 more source

VHH-based CAR-T cells targeting Claudin 18.2 show high efficacy in pancreatic cancer models. [PDF]

Front Immunol
Xing Y, Shi G, Li Z, Liu X, Nie L, Zhang Y, Song Y, Sun S, Chan MKS, Wong MBF, Casazza K, Lakey JRT, Chen Y, Zhu X, Feng Y.   +14 more
europepmc   +1 more source

Membership‐Making in Diverse Societies: Revisiting the Idea of Society as a Common Possession

Journal of Applied Philosophy, EarlyView.
ABSTRACT The traditional aim of Western social democracy has been to create a society that is a ‘common possession’ of its members (in T.H. Marshall's words). Social democratic politics has therefore been both society‐making and membership‐making, orienting people to a shared society as an object of attachment and loyalty, and nurturing membership ...
Will Kymlicka
wiley   +1 more source

Nanobodies: From Discovery to AI-Driven Design. [PDF]

Biology (Basel)
Zhu H, Ding Y.
europepmc   +1 more source

Defining the Patient Journey and Identifying Digital Health Solutions in Treatment-Resistant Schizophrenia. [PDF]

Actas Esp Psiquiatr
Grasa E, Forment A, Alonso-Solís A, Ramalho L, Roldán A, Pousa E, Aussó S, Berdun J, Genova Tesoro A, Escudero J, Corripio I.   +10 more
europepmc   +1 more source