Results 271 to 280 of about 95,544 (345)

Characteristics and Clinical Outcomes of Patients With Hidradenitis Suppurativa (HS) Treated With Bimekizumab: A Canadian Retrospective Chart Review

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Hidradenitis suppurativa (HS) is a chronic, recurrent inflammatory skin disease characterised by painful nodules, abscesses, and draining and non‐draining tunnels. Currently, there are two biologics approved in Canada for the treatment of moderate‐to‐severe HS, adalimumab (anti‐TNF) and secukinumab (anti‐IL‐17A).
Irina Turchin   +4 more
wiley   +1 more source

VHH-based CAR-T cells targeting Claudin 18.2 show high efficacy in pancreatic cancer models. [PDF]

open access: yesFront Immunol
Xing Y   +14 more
europepmc   +1 more source

New Biologic and Small Molecule Therapies for Hidradenitis Suppurativa

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Hidradenitis suppurativa (HS) is an inflammatory skin disease that has historically been underdiagnosed and, until recently, under‐researched. Furthermore, the pathophysiology of HS is complex, and not fully understood. Just three biologic medications—adalimumab (anti‐TNF‐α), secukinumab (anti‐IL17A) and bimekizumab (anti‐IL17A/F) are licensed
Emily Pender   +2 more
wiley   +1 more source

SITA: Predicting site-specific immunogenicity for therapeutic antibodies. [PDF]

open access: yesJ Pharm Anal
Cun Y   +9 more
europepmc   +1 more source

Circ_0006174 Drives Triple Negative Breast Cancer Progression and Immune Escape Through Regulating miR‐3139/PD‐L1 Axis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) is characterized as an aggressive malignancy with limited therapeutic options. The circular RNA circ_0006174 has been implicated in oncogenic processes across various cancers; however, its specific role in the pathogenesis of TNBC remains unclear.
Yong‐Zhe Tang   +4 more
wiley   +1 more source

Defining the Patient Journey and Identifying Digital Health Solutions in Treatment-Resistant Schizophrenia. [PDF]

open access: yesActas Esp Psiquiatr
Grasa E   +10 more
europepmc   +1 more source

Building Successful Team Interaction in Online Team Coaching Process: A Case Study

open access: yesKnowledge and Process Management, EarlyView.
ABSTRACT In the post‐COVID‐19 era, work has expanded to multiple locations with teams operating increasingly online, where successful team interaction between colleagues is a more challenging task. Thus, this study explores factors in online team coaching that build successful team interaction.
Eija‐Liisa Heikka   +1 more
wiley   +1 more source

Experiences of Humanizing Care in Nursing Students-A Phenomenological Study. [PDF]

open access: yesHealthcare (Basel)
Dávila MFV   +3 more
europepmc   +1 more source

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