Results 31 to 40 of about 2,575,597 (213)
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
The American Biology Teacher, 2012 Who are we? The question of human nature seems to haunt all disciplines. That may tell us how very “human” the question is. Answers vary widely. Yet scientists—anthropologists, geneticists, ethologists, and developmental and evolutionary biologists—rely on observations and empirical data. Their conclusions thus seem more objective. Biologically, humans
openaire +2 more sources
Humanitarianism, humanity, human [PDF]
Journal of Human Rights, 2003 (2003). Humanitarianism, humanity, human. Journal of Human Rights: Vol. 2, No. 2, pp. 253-258.
openaire +2 more sources
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source
Pancreaticoduodenal transplantation in humans [PDF]
, 1984 Whole cadaveric pancreata were transplanted to the pelvic extraperitoneal location in four patients with diabetes who previously had undergone successful cadaveric renal transplantation.
Diliz-Pere, H +8 more
core
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Human-robot co-manipulation of extended objects: Data-driven models and control from analysis of human-human dyads [PDF]
arXiv, 2020 Human teams are able to easily perform collaborative manipulation tasks. However, for a robot and human to simultaneously manipulate an extended object is a difficult task using existing methods from the literature. Our approach in this paper is to use data from human-human dyad experiments to determine motion intent which we use for a physical human ...
arxiv
The interaction between humans and knowledge management systems : rethinking the future [PDF]
, 2019 In this workshop position paper, we propose a study to understand the importance of knowledge management systems among academics in Saudi higher education institutions, admitting that knowledge workers and Knowledge Management Systems are valuable ...
Almujally, Nouf, Joy, Mike
core
Olfactory Orientation and Navigation in Humans. [PDF]
, 2015 Although predicted by theory, there is no direct evidence that an animal can define an arbitrary location in space as a coordinate location on an odor grid. Here we show that humans can do so. Using a spatial match-to-sample procedure, humans were led to
Arter, Jennifer +3 more
core +4 more sources
Human to human transmission of H7N9 [PDF]
BMJ, 2013 Since the new avian influenza virus, H7N9, first emerged in China, a primary concern has been whether it might spread between humans. The vast majority of the 133 confirmed cases reported so far seem to be epidemiologically unconnected, with many patients reporting a recent history of exposure to live poultry, which are suspected to be a main reservoir
James W. Rudge +2 more
openaire +2 more sources