Results 81 to 90 of about 19,747,875 (398)

Could humans recognize odor by phonon assisted tunneling? [PDF]

open access: yes, 2006
Our sense of smell relies on sensitive, selective atomic-scale processes that are initiated when a scent molecule meets specific receptors in the nose. However, the physical mechanisms of detection are not clear.
A. M. Stoneham   +16 more
core   +2 more sources

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

Network structure shapes the impact of diversity in collective learning

open access: yesScientific Reports
It is widely believed that diversity arising from different skills enhances the performance of teams, and in particular, their ability to learn and innovate.
Fabian Baumann   +2 more
doaj   +1 more source

Desobediencia: ¿Derecho o estrategia? A propósito de la reivindicación de la “política de desobediencia civil” en Catalunya

open access: yesTeoria Jurídica Contemporânea, 2018
RESUMEN: Aunque la tradición de la desobediencia civil y, más lejos aún, la del derecho a resistencia tiene antecedentes muy claros, hoy se ha producido un giro.
Javier de Lucas
doaj   +1 more source

Would humans without language be apes? [PDF]

open access: yes, 2003
The bedrock of comparative psychology of cognition, especially where nonhuman primates are concerned, rests on Darwin's famous account according to which continuity would be the main trait leading from the animal to the human mind.
Vauclair, J
core  

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Human Rights, Human Needs, Human Development, Human Security: elations ships between Four International ‘Human’ Discourses

open access: yesForum for Development Studies, 2007
Human rights, human development and human security form increasinglyimportant, partly interconnected, partly competitive and misunderstood ethicaland policy discourses. Each tries to humanize a pre-existing and unavoidablemajor discourse of everyday life, policy and politics; each has emerged withinthe United Nations world; each relies implicitly on a ...
openaire   +2 more sources

Veterinary science : humans, animals and health [PDF]

open access: yes, 2011
This living book is a collection of open access materials bringing scientific papers to a humanities ...
Fudge, Erica, Palmer, Clare
core  

The limits of human predictions of recidivism. [PDF]

open access: yes, 2020
Dressel and Farid recently found that laypeople were as accurate as statistical algorithms in predicting whether a defendant would reoffend, casting doubt on the value of risk assessment tools in the criminal justice system.
Goel, Sharad   +3 more
core  

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