Results 81 to 90 of about 10,847,213 (333)

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Humans, Humanities, and Humanism in an Age of Technology [PDF]

open access: yes, 2016
Harry Potter’s world as described by J.K. Rowling in a series of books for children is not the world of us, ordinary humans.1 Owls delivering letters overnight would be handy. Howling letters that criticize their recipients in public might be embarrassing.
openaire   +3 more sources

Human niche, human behaviour, human nature [PDF]

open access: yesInterface Focus, 2017
The concept of a ‘human nature’ or ‘human natures’ retains a central role in theorizing about the human experience. InHomo sapiensit is clear that we have a suite of capacities generated via our evolutionary past, and present, and a flexible capacity to create and sustain particular kinds of cultures and to be shaped by them.
openaire   +3 more sources

Veterinary science : humans, animals and health [PDF]

open access: yes, 2011
This living book is a collection of open access materials bringing scientific papers to a humanities ...
Fudge, Erica, Palmer, Clare
core  

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

Learning Representations by Humans, for Humans

open access: yes, 2019
We propose a new, complementary approach to interpretability, in which machines are not considered as experts whose role it is to suggest what should be done and why, but rather as advisers. The objective of these models is to communicate to a human decision-maker not what to decide but how to decide.
Banaji , Mahzarin   +4 more
openaire   +5 more sources

Strange Loops: Apparent versus Actual Human Involvement in Automated Decision-Making [PDF]

open access: yes, 2019
The era of AI-based decision-making fast approaches, and anxiety is mounting about when, and why, we should keep “humans in the loop” (“HITL”). Thus far, commentary has focused primarily on two questions: whether, and when, keeping humans involved will ...
Brennan-Marquez, Kiel   +2 more
core   +1 more source

Humans perceive flicker artifacts at 500 Hz. [PDF]

open access: yes, 2015
Humans perceive a stable average intensity image without flicker artifacts when a television or monitor updates at a sufficiently fast rate. This rate, known as the critical flicker fusion rate, has been studied for both spatially uniform lights, and ...
Davis, James   +2 more
core   +2 more sources

Purification tags markedly affect self‐aggregation of CPEB3

open access: yesFEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito   +6 more
wiley   +1 more source

Explorations in engagement for humans and robots [PDF]

open access: yes, 2005
This paper explores the concept of engagement, the process by which individuals in an interaction start, maintain and end their perceived connection to one another.
Kidd, Cory   +4 more
core   +5 more sources

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