Results 171 to 180 of about 20,060 (198)
Langerhans Cell Histiocytosis With MAP2K1E102_I103del Mutation Successfully Treated With Trametinib
eJHaem, Volume 6, Issue 3, June 2025.ABSTRACT The discovery of the MAPK pathway mutations in lesions of patients with Langerhans cell histiocytosis (LCH) has made targeted therapy an important therapeutic approach for these patients. Theoretically, the RAF‐independent mutation MAP2K1E102_I103del is naturally resistant to allosteric MEK inhibitors.
Min Lang, Long Chang, Xin‐xin Cao
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Psychiatry and Clinical Neurosciences Reports, Volume 4, Issue 2, June 2025.This study aimed to assess the efficacy and safety of SDT‐001, a digital therapeutic, in Japanese children and adolescents with attention‐deficit/hyperactivity disorder (ADHD). The SDT‐001 group tended to show a greater change from baseline in the ADHD‐RS‐IV scores than the single‐task group, but this difference was not statistically significant ...
Katsunaka Mikami +6 more
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Medical Journal of Australia, Volume 222, Issue 9, Page 472-480, May 2025.Abstract Introduction This updated guideline replaces the previous Royal Australian College of General Practitioners and Osteoporosis Australia (now, Healthy Bones Australia) guideline from 2017. The accumulation of high quality evidence supporting improvements in clinical practice over the past five years, need for expert consensus and opinion, and ...
Peter Wong +6 more
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Advanced Science, Volume 12, Issue 18, May 15, 2025.This study develops RPTH by re‐modifying teriparatide and designs a biomimetic microstructured scaffold (BMRP) loaded with RPTH to address osteoporotic tendon‐to‐bone interface repair. The BMRP restores tissue architecture by balancing bone homeostasis and remodeling the microstructure, achieving functional recovery in an osteoporotic rotator cuff tear
Chengzhong Xu +11 more
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American Journal of Human Biology, Volume 37, Issue 5, May 2025.ABSTRACT Introduction The objectives of this investigation were to study puberty in medieval adolescents from northern Spain and use funerary archaeology data to explore the social implications of adolescence within this community. Method The pubertal development of 37 skeletons (aged 8–25 years) from Marialba de la Ribera (León, Spain, 3rd to 15th ...
Danielle M. Doe +4 more
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Clinical Case Reports, Volume 13, Issue 5, May 2025.ABSTRACT Renal cell carcinoma, a highly recurrent and metastatic malignancy. Drawing upon a decade‐long expertise in managing recurrent cases, we advocate the adoption of Programmed Death‐1 (PD‐1) inhibitors in conjunction with Axitinib when monotherapy with Axitinib fails to restrain tumor metastasis, thereby empowering doctors with an efficacious ...
PengNan Hu, Di Chen, Jun Yu, Hua Mi
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27. Dislocation of the Humerus backwards into the Infra-spinous Fossa [PDF]
NULL AUTHOR_ID
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Clinical Case Reports, Volume 13, Issue 5, May 2025.ABSTRACT Cryptococcal meningitis in non‐HIV patients and comorbid with Guillain‐Barré syndrome is rare. Accurate diagnosis necessitates a comprehensive understanding of historical records, laboratory workup, and a heightened index of suspicion, coupled with prompt and comprehensive combined therapy.
Liu L. Yang +4 more
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Clinical Profile of Pediatric Solid Tumors: Experience From a Tertiary Care Center in Ethiopia
Cancer Reports, Volume 8, Issue 5, May 2025.ABSTRACT Background Pediatric solid tumors are a significant health challenge worldwide, especially in low‐ and middle‐income countries such as Ethiopia, where healthcare infrastructure is limited and treatment modalities are scarce. Aims This study aims to understand the epidemiological characteristics of these tumors and short‐term treatment outcomes.
Mamude Dinkiye +4 more
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Effects of life history strategies and habitats on limb regeneration in plethodontid salamanders
Developmental Dynamics, Volume 254, Issue 5, Page 396-419, May 2025.Abstract Background Salamanders are the only tetrapods that exhibit the ability to fully regenerate limbs. The axolotl, a neotenic salamander, has become the model organism for regeneration research. Great advances have been made providing a detailed understanding of the morphological and molecular processes involved in limb regeneration.
Vivien Bothe +3 more
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