Results 51 to 60 of about 666 (215)

Transcriptomic Analysis of Polyhexamethyleneguanidine-Induced Lung Injury in Mice after a Long-Term Recovery

open access: yesToxics, 2021
Polyhexamethyleneguanidine phosphate (PHMG-P) is one of the causative agents of humidifier disinfectant-induced lung injury. Direct exposure of the lungs to PHMG-P causes interstitial pneumonia with fibrosis.
Jeongah Song   +5 more
doaj   +1 more source

Effects of a mixture of chloromethylisothiazolinone and methylisothiazolinone on peripheral airway dysfunction in children. [PDF]

open access: yesPLoS ONE, 2017
Children who were only exposed to a mixture of chloromethylisothiazolinone (CMIT) and methylisothiazolinone (MIT) as humidifier disinfectant (HD) components were evaluated for humidifier disinfectant-associated lung injury (HDLI) from 2012.
Hyun-Ju Cho   +7 more
doaj   +1 more source

Lung Transplantation for Chronic Humidifier Disinfectant-Associated Lung Injury [PDF]

open access: yesKorean Journal of Critical Care Medicine, 2016
In the spring of 2011, a cluster of lung injuries caused by humidifier disinfectant (HD) usage were reported in Korea. Many patients required mechanical ventilation, extracorporeal membrane oxygenation, and even lung transplantation (LTPL).
Won-Young Kim   +8 more
doaj   +1 more source

Flexible-Imaging-Fiber-Guided Intratracheal Intubation in Rodents

open access: yesApplied Sciences, 2023
Although experiments on intratracheal intubation for animals are essential for research, it remains challenging. This study aimed to validate an animal model using a flexible imaging guide system that can be conveniently and safely used as a new method ...
Sang Hoon Jeong   +8 more
doaj   +1 more source

Humidifier Disinfectant–associated Children’s Interstitial Lung Disease

open access: yesAmerican Journal of Respiratory and Critical Care Medicine, 2014
Abstract Rationale Beginning in 2006, epidemics of a fatal lung injury of unknown cause in children were observed in Korea every spring. A recent study demonstrated that this type of children’s interstitial lung disease (chILD) is associated with humidifier disinfectant use.
Kyung Won, Kim   +33 more
openaire   +3 more sources

Mitochondria disease due to humidifier disinfectants: diagnostic criteria and its evidences [PDF]

open access: yesEnvironmental Analysis Health and Toxicology, 2020
Humidifier disinfectant damages caused by the misuse of humidifier disinfects, such as polyhexamethylene guanidine (PHMG), resulted in chemical disasters in South Korea in 2011. About four million people were exposed to humidifier disinfectants (HDs) in the 17 years between 1994 and 2011.
Jong Han Leem, Hwan-Cheol Kim
openaire   +2 more sources

Inhalation Lung Injury Associated with Humidifier Disinfectants in Adults

open access: yesJournal of Korean Medical Science, 2016
We recently established a novel disease entity presented as progressive respiratory failure associated with the inhalation of humidifier disinfectants. In April 2011, we encountered a series of peripartum patients with complaints of respiratory distress of unknown etiology, which was an uncommon phenomenon.
Jin-Won Huh   +9 more
openaire   +2 more sources

Comprehensive analysis of adverse outcome pathway, potency, human exposure supports carcinogenicity of polyhexamethylene guanidine phosphate in lung cancer

open access: yesEcotoxicology and Environmental Safety
In this study, we investigated the potential mechanisms by which polyhexamethylene guanidine phosphate (PHMG-p), a known respiratory irritant, may contribute to lung cancer development.
Yong Joo Park   +7 more
doaj   +1 more source

Magnesium‐Based Transient Bioelectronics, Bio‐Optics and Bio‐Scaffolds

open access: yesAdvanced Functional Materials, EarlyView.
This paper reviews the state of the art and recent advances in magnesium‐based thin‐film, foils, and scaffolds for applications in transient bio‐optics, bioelectronics and tissue engineering. The design principles, fabrication methods, material properties, and integration strategies are discussed in detail.
Massimo Mariello, Yves Leterrier
wiley   +1 more source

Polyhexamethylene guanidine phosphate induces epithelial-to-mesenchymal transition and cancer stem cell-like properties via Wnt/β-catenin signaling in human bronchial epithelial cells

open access: yesEcotoxicology and Environmental Safety
Inhalation exposure to polyhexamethylene guanidine phosphate (PHMG-p), a primary component of humidifier disinfectants, has been linked to interstitial lung disease and potential carcinogenic effects.
Gi Ho Lee   +5 more
doaj   +1 more source

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