Results 201 to 210 of about 815 (248)

Cascade Therapy of Periodontitis via Sequential Release of Ribosome‐Targeting Antimicrobial Peptide and Irisin From a Multifunctional MOF‐Based System

Advanced Science, EarlyView.
This study presents a novel strategy for periodontitis treatment by co‐delivering a membrane‐ and ribosome‐targeting antimicrobial peptide GF and Irisin through a pH‐responsive metal‐organic framework. The system enables sequential release, providing rapid antibacterial action, anti‐inflammatory and antioxidative effects, as well as promoting bone ...
Yan Chen, Zheng Xu, Yunmo Xue, Shanshan Liu, Xiang Zhang, Jingyao Guo, Minhui Yao, Yue Liu, Xiaolin Lu, Jieshu Qian, Qian Ma   +10 more
wiley   +1 more source

ROS‐Responsive Wedelolactone Hydrogel Promotes Intervertebral Disc Repair by Disrupting the NF‐κB–LCN2 Inflammatory Feedback Loop

Advanced Science, EarlyView.
A mechanically robust, ROS‐responsive hydrogel is engineered to treat intervertebral disc degeneration by targeting the NF‐κB–LCN2 inflammatory feedback loop. By delivering wedelolactone specifically within oxidative niches, this system disrupts macrophage–disc cell crosstalk.
Zimei Wu, Yan Xu, Lang Qin, Zemin Ling, Yingjie Mai, Xiong Tian Guo, Jiajia Chen, Leping Yan, Lin Wang, Liming Bian, Fuxin Wei   +10 more
wiley   +1 more source

Metformin‐Based Covalent Organic Frameworks With Excellent Biosafety and High Efficiency against Pathogenic Microorganisms

Advanced Science, EarlyView.
This work presents the first metformin‐based COFs featuring built‐in biosafety and a unique triple‐synergy mechanism. This scalable platform achieves broad‐spectrum eradication of bacteria and viruses, enabling reusable protective membranes with exceptional biocompatibility for advanced biomedical applications and personal protection.
Jia‐Yi Liu, Hong Jiang, Lei Ma, Jin‐Yi Yu, Ming‐Yi Yang, Hao‐Ru Wang, Jun‐Yuang Tang, Shengfeng Huang, Wei Yi, Meng Lu, Ya‐Qian Lan, Xu‐Jia Hong   +11 more
wiley   +1 more source

Nucleoside‐Based Hydrogel Platform Synergizes with Photothermal Effects for Enhanced Biofilm Eradication Against Periodontitis

Advanced Science, EarlyView.
A synergistic antibiofilm hydrogel platform (ZBAg@FNP) is developed by encapsulating an organic small‐molecule photothermal agent (FNP) within a silver ion‐mediated supramolecular hydrogel (ZBAg), enabling photothermal disruption of biofilm integrity and controlled Ag⁺ ion release upon irradiation.
Yinghui Wen, Yunfei Li, Tiannan Liu, Chongkui Sun, Hang Zhao, Yao Yuan, Shiping Yang, Tingxing Zhao, Jiang Liu   +8 more
wiley   +1 more source

Defect‐Rich 2D Layered Double Hydroxides Enhance Sonodynamic Antibacterial Therapy

Advanced Science, EarlyView.
This study develops defect‐rich ultrathin ZnCuW‐LDH nanosheets (DR‐ZnCuW‐LDH) via acid etching. DR‐ZnCuW‐LDH exhibits fourfold enhanced US‐triggered ROS production due to oxygen defects and electronic modulation, demonstrating potent antibacterial efficacy in vitro/vivo.
Qian Liu, Yu Yang, Rui Zhao, Linwei Huang, Xingyu Qi, Min Wu, Jianliang Shen   +6 more
wiley   +1 more source

Evaluation of phage-based decontamination in respiratory intensive care unit environments using ddPCR and 16S rRNA targeted sequencing techniques. [PDF]

Front Cell Infect Microbiol
Shi Y, Zhang W, Li L, Wu W, Li M, Xiao K, Wang K, Sheng Z, Xie F, Wang X, Shi X, Tong Y, Xie L.   +12 more
europepmc   +1 more source

A Guideline to Evaluate Sorbent Performance for Atmospheric Water Harvesting

Advanced Energy and Sustainability Research, EarlyView.
Reporting guidelines for atmospheric water harvesting sorbents allow benchmarking between research groups across seven key performance indicators (KPIs). Beyond simple equilibrium values (such as capacity or maximum water uptake), these KPIs validate sensitivity, reversibility, regeneration conditions, chemical stability, kinetics, and water quality ...
Simon Ponton, David Brassard, Andrés Felipe Sánchez Rendón, Seyedemad Alavitabari, Richard Boudreault, Emilie Bédard, Pierre‐Luc Girard‐Lauriault, Jason R. Tavares   +7 more
wiley   +1 more source

Current Landscape: Use of Supercritical CO2 in the Wood Industry

Advanced Energy and Sustainability Research, EarlyView.
The application of supercritical carbon dioxide (scCO2) to successfully dewater as well as extract resin from wood is becoming increasingly popular due to its greener and less energy‐intensive approach. With world focus shifting to developing methods with greater efficiency while decreasing harm to the environment, scCO2 applications have begun to set ...
Anthony Dahdah, Subashani Maniam
wiley   +1 more source

Enhancing Lesion Detection in Rat CT Images: A Deep Learning-Based Super-Resolution Study. [PDF]

Biomedicines
Ham S, Jeong SH, Lee H, Nam YJ, Lee H, Choi JY, Lee YS, Park YH, Park SA, Kim W, Choi H, Kim H, Lee JH, Kim C.   +13 more
europepmc   +1 more source

Rethinking Power Solutions for Healthcare Wearables: From Point‐of‐Care and Episodic use to Continuous Monitoring and Therapeutic Platforms

Advanced Energy and Sustainability Research, EarlyView.
This Perspective examines practical power solutions for wearable healthcare systems, highlighting the limits of standard batteries. It categorizes wearables into four domains—point‐of‐care diagnostics, episodic monitoring, continuous long‐term monitoring, and therapeutic platforms—and analyzes their power needs.
Seokheun Choi
wiley   +1 more source