Results 131 to 140 of about 15,911 (332)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Improving Newborn Health in Countries Exposed to Political Violence: An Assessment of the Availability, Accessibility, and Distribution of Neonatal Health Services at Palestinian Hospitals

open access: yesJournal of Multidisciplinary Healthcare, 2020
Salwa Massad,1 Marina Tucktuck,2 Ranin Dar Khawaja,3,4 Hadil Dalloul,1 Khalid Abu Saman,1 Rand Salman,1 Rawan Kafri,1 Hatem Khammash5,6 1Research Unit, Palestinian National Institute of Public Health, Ramallah, Palestine; 2School of Medicine, St.
Massad S   +7 more
doaj  

Refrigeration, air conditioning, and warm air heating equipment : 1999 [PDF]

open access: yes, 2000
Current industrial report. Contains annual data for refrigeration, air conditioning, and warm air heating equipment produced in the United ...

core  

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Non-Humidified Fuel Cells Using a Protic Ionic Liquid as Electrolyte [PDF]

open access: bronze, 2012
Tomohiro YASUDA   +4 more
openalex   +1 more source

Static feed water electrolysis module [PDF]

open access: yes
An advanced static feed water electrolysis module (SFWEM) and associated instrumentation for generating breathable O2 was developed. The system also generates a H2 byproduct for use in an air revitalization system for O2 recovery from metabolic CO2 ...
Jensen, F. C.   +2 more
core   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Results of DEC Unit Assisted by Solar Energy in Lisbon [PDF]

open access: yes, 2009
The Air Handling Unit (AHU) with Desiccant Evaporative Cooling (DEC) technology, assisted by solar energy, is in operation at LNEG (former INETI) since 1999, ant it has some features in its design, resulting from local constraints of the building and ...
Mendes, J. Farinha   +2 more
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

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