Results 101 to 110 of about 581,410 (303)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Temperature and Humidity Monitoring System in Broiler Poultry Farm

, 2020
Irving Vitra Paputungan, Abidurrahman Al Faruq, Fitri Puspasari, Furqaan Al Hakim, Imam Fahrurrozi, Unan Yusmaniar Oktiawati, Iing Mutakhiroh   +6 more
openalex   +1 more source

Temperature- and humidity-induced changes in alum-treated wood: a qualitative X-ray diffraction study [PDF]

, 2018
Caitlin M. A. McQueen, Calin Constantin Steindal, O. Narygina, Susan Braovac   +3 more
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Agricultural Economic Water Productivity Differences across Counties in the Colorado River Basin

Hydrology
This study estimates the relative contribution of different factors to the wide variation in agricultural economic water productivity (EWP) across Colorado River Basin counties.
George B. Frisvold, Jyothsna Atla
doaj   +1 more source

Design of a water condensation system from air humidity on the island of San Andrés

, 2023
Jay Barker, Lilit Danisha
openalex   +1 more source

Assessing the Effects of Temperature and Relative Humidity on the Signal Strength of We FM Abuja, Nigeria During Harmattan Period [PDF]

, 2018
Ale Felix, Abdullahi Ayegba, John Yakubu
openalex   +1 more source

Hygrothermal characterization of rammed earth according to humidity variations [PDF]

, 2023
Alessia Emauela Losini, Taini Chitimbo, Laura Létévé, Monika Woloszyn, Anne‐Cécile Grillet, Noémie Prime   +5 more
openalex   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source