Results 61 to 70 of about 581,410 (303)

Research on the temperature and humidity distribution characteristics in potato storage facilities: experimental analysis and numerical simulation

Frontiers in Sustainable Food Systems
Potatoes rank among the world’s most important food crops. Traditional storage methods often lack precise environmental control, rendering potatoes vulnerable to rot and spoilage.
Qi Zhen, Qi Zhen, Chao Xu, Tana, Hongzhi Wang, Xinwei Yue, Caixia Yan, Caixia Yan, Yunfeng Sun   +8 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Water-enhanced CO2 capture in metal–organic frameworks

Frontiers in Chemistry
CO2 capture from post-combustion flue gas originating from coal or natural gas power plants, or even from the ambient atmosphere, is a promising strategy to reduce the atmospheric CO2 concentration and achieve global decarbonization goals.
Celine Cammarere, Jaeden Cortés, T. Grant Glover, Randall Q. Snurr, Joseph T. Hupp, Jian Liu, Jian Liu   +6 more
doaj   +1 more source

vQRS Based on Hybrids of CNT with PMMA-POSS and PS-POSS Copolymers to Reach the Sub-PPM Detection of Ammonia and Formaldehyde at Room Temperature Despite Moisture

Chemosensors, 2017
Nanocomposite-based quantum resistive vapour sensors (vQRS) have been developed from the assembly of hybrid copolymers of polyhedral oligomeric silsesquioxane (POSS) and poly(methyl methacrylate) (PMMA) or poly(styrene) (PS) with carbon nanotubes (CNT ...
Abhishek Sachan, Mickael Castro, Veena Choudhary, Jean-François Feller   +3 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Aerial root formation in Oaxacan maize (Zea mays) landraces persists into the adult phase and is minimally affected by soil nitrogen and ambient humidity

Frontiers in Plant Science
Maize (Zea mays L.) is the most widely produced crop in the world, and conventional production requires significant amounts of synthetic nitrogen fertilizer, which has negative economic and environmental consequences. Maize landraces from Oaxaca, Mexico,
Rafael E. Venado, Jennifer Wilker, Valentina Infante, Caitlin McLimans, Fletcher Robbins, Fletcher Robbins, Courtney Phillips, Claudia Irene Calderón, Claudia Irene Calderón, Jason G. Wallace, Jason G. Wallace, Jason G. Wallace, Jean-Michel Ané, Jean-Michel Ané   +13 more
doaj   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Thermophysical Coefficients of Mustard Seeds Grain-Air Mixture under High-Temperature Conditions

Сельскохозяйственные машины и технологии
The paper highlights that modeling the drying process of mustard seed samples using thermogravimetric moisture measurement enables the identification of the most effective design options for drying chambers.
A. P. Evdokimov, A. A. Leshchenko
doaj   +1 more source

The study of the relationship between thermal conductivity and porosity, permeability, humidity of sedimentary rocks of the West Siberian Plate

Georesursy, 2018
The determination of correlation between thermal conductivity and structural parameters (porosity, permeability, humidity) of sedimentary rocks is a very urgent task. This article analyzes and compares the results of measurements of these parameters for ~
A.D. Duchkov, D.E. Ayunov, S.V. Rodyakin, P.A. Yan   +3 more
doaj   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source