Results 61 to 70 of about 881,291 (289)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Humidity-Driven Transparent Holographic Free-Standing Polyelectrolyte Films
, 2020 In the present work, transparent holographic poly(diallyldimethylammonium chloride) (PDADMAC)/heparin and PDADMAC/poly(styrenesulfonate) (PSS) films were synthesized via polyelectrolyte coacervates.
Sviatlana A. Ulasevich +15 more
core +2 more sources
Geophysical Research Letters, 2023 Dust aerosols are produced by wind erosion, and it is widely accepted that dust aerosols can be produced only if the wind speed exceeds a certain threshold velocity, which is largely controlled by soil moisture content.
Xiewen Ma +7 more
doaj +1 more source
Humidity-Driven Color-Fluorescence Dual Switching of Naphthalenediimide Aggregates
, 2023 Numerous emerging applications require precise monitoring of humidity that is not only sensitive and miniaturized but also durable and portable. However, except for the existing sensing mechanisms, such as resistive, capacitive, impedance, and voltage ...
Yang-Hui Luo +9 more
core +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
The Shape of Humidity: Performing Black Atlantic Theory Making
Performance Philosophy, 2019 Following bell hooks’ submission that theory making is “a location for healing” (2017, 59) “The Shape of Humidity: Performing Black Atlantic Theory Making” riffs upon the historically critical and widely circulated subject of the black body politic and ...
Genevieve Hyacinthe
doaj +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Durability study of ramie fiber fabric reinforced phenolic plates under humidity conditions
Science and Engineering of Composite Materials, 2016 A durability study of a ramie fiber fabric reinforced phenolic resin (RFRP) plate under 50%, 85%, and 98% relative humidity for 6 months at room temperature was performed.
Xian Guijun +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source