Results 61 to 70 of about 564,713 (260)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Chitosan-Based Highly Sensitive Viable Humidity Sensor for Human Health Monitoring

ACS Omega, 2023
Parvesh Kumari, Ankit Kumar, Aditya Yadav, Govind Gupta, Gaurav Gupta, Dilip D. Shivagan, Komal Bapna   +6 more
doaj   +1 more source

Research on the temperature and humidity distribution characteristics in potato storage facilities: experimental analysis and numerical simulation

Frontiers in Sustainable Food Systems
Potatoes rank among the world’s most important food crops. Traditional storage methods often lack precise environmental control, rendering potatoes vulnerable to rot and spoilage.
Qi Zhen, Qi Zhen, Chao Xu, Tana, Hongzhi Wang, Xinwei Yue, Caixia Yan, Caixia Yan, Yunfeng Sun   +8 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Water-enhanced CO2 capture in metal–organic frameworks

Frontiers in Chemistry
CO2 capture from post-combustion flue gas originating from coal or natural gas power plants, or even from the ambient atmosphere, is a promising strategy to reduce the atmospheric CO2 concentration and achieve global decarbonization goals.
Celine Cammarere, Jaeden Cortés, T. Grant Glover, Randall Q. Snurr, Joseph T. Hupp, Jian Liu, Jian Liu   +6 more
doaj   +1 more source

vQRS Based on Hybrids of CNT with PMMA-POSS and PS-POSS Copolymers to Reach the Sub-PPM Detection of Ammonia and Formaldehyde at Room Temperature Despite Moisture

Chemosensors, 2017
Nanocomposite-based quantum resistive vapour sensors (vQRS) have been developed from the assembly of hybrid copolymers of polyhedral oligomeric silsesquioxane (POSS) and poly(methyl methacrylate) (PMMA) or poly(styrene) (PS) with carbon nanotubes (CNT ...
Abhishek Sachan, Mickael Castro, Veena Choudhary, Jean-François Feller   +3 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Aerial root formation in Oaxacan maize (Zea mays) landraces persists into the adult phase and is minimally affected by soil nitrogen and ambient humidity

Frontiers in Plant Science
Maize (Zea mays L.) is the most widely produced crop in the world, and conventional production requires significant amounts of synthetic nitrogen fertilizer, which has negative economic and environmental consequences. Maize landraces from Oaxaca, Mexico,
Rafael E. Venado, Jennifer Wilker, Valentina Infante, Caitlin McLimans, Fletcher Robbins, Fletcher Robbins, Courtney Phillips, Claudia Irene Calderón, Claudia Irene Calderón, Jason G. Wallace, Jason G. Wallace, Jason G. Wallace, Jean-Michel Ané, Jean-Michel Ané   +13 more
doaj   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source