Results 101 to 110 of about 1,002,942 (309)
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Multitarget control models for building thermal comfort and indoor air quality - A critical review
Results in EngineeringThe control techniques in buildings contribute significantly to thermal comfort and indoor air quality (IAQ). However, the gaps are existing for multitarget controls considering both thermal comfort and IAQ.
Yanfei Li +7 more
doaj +1 more source
Open-source digital technologies for low-cost monitoring of historical constructions [PDF]
, 2017 This paper shows new possibilities of using novel, open-source, low-cost platforms for the structural health monitoring of heritage structures. The objective of the study is to present an assessment of increasingly available open-source digital modeling ...
Basto, Camilo +2 more
core +2 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Gypsum-Based Humidity-Control Material: Preparation, Performance and Its Impact on Building Energy Consumption. [PDF]
Materials (Basel), 2023 Li X, Ran M.
europepmc +1 more source
Moisture condensation on building envelopes in differential ventilated spaces in the tropics: quantitative assessment of influencing factors [PDF]
, 2016 Ventilation systems play a significant role in maintaining the indoor thermal and hygric balance. Nevertheless, the systems had been implicated to result in many problems.
Boji +16 more
core +2 more sources
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
RANCANG BANGUN ALAT PENGKONDISI SUHU RUANGAN DAN KELEMBAPAN UDARA PADA TANAMAN JAMUR BERBASIS IOT MENGGUNAKAN ARDUINO UNO [PDF]
Fungi are plants that have nuclei and spores and do not contain chlorophyll in the form of cells or branch threads. Fungi lack chlorophyll, so they consume food made by other dead organisms. Growing oyster mushrooms provides several benefits.
Prasetya, Dava Dwi Lesmana
core
Agenator: An open source computer-controlled dry aging system for beef [PDF]
, 2019 Dry aging of beef is a process where beef is exposed to a controlled environment with the ultimate goal of drying the beef to improve its quality and value.
Calkins, Chris R. +3 more
core +1 more source