Results 131 to 140 of about 1,012,376 (308)
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao +6 more
wiley +1 more source
Within high-precision indoor environments, such as semiconductor fabrication or textile plants, humidity control is paramount for preserving product integrity and reducing energy expenditure.
Xiaojun Ma +3 more
doaj +1 more source
Simulation of a model-based optimal controller for heating systems under realistic hypothesis [PDF]
An optimal controller for auxiliary heating of passive solar buildings and commercial buildings with high internal gains is tested in simulation. Some of the most restrictive simplifications that were used in previous studies of that controller (Kummert ...
Andre, Philippe, Kummert, Michael
core
Temperature-Controlled Humid Storage Room
The design of a soil sample storage room that has been in operation since 1954 is described. The room provides a storage environment with a constant temperature of 55 °F and relative humidities of 90 – 97 percent. It is of wood frame construction, lined with copper sheeting, forming a watertight interior.
openaire +3 more sources
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Method of evaluating moisture barrier properties of encapsulating materials Patent [PDF]
Method of evaluating moisture barrier properties of materials used in electronics ...
Ellern, W. B.
core +1 more source
Objective The study aimed to identify symptom‐based predictors of dry eye disease (DED) signs in the Sjögren's International Collaborative Clinical Alliance (SICCA) cohort. Methods We performed a retrospective analysis examining 16 ocular symptoms (most graded 0–4) and artificial tear (AT) use (graded 0–3) as predictors of DED signs (abnormal ocular ...
Pragnya R. Donthineni +7 more
wiley +1 more source
Strain rate, temperature, and humidity on strength and moduli of a graphite/epoxy composite [PDF]
Results of an experimental study of the influence of strain rate, temperature and humidity on the mechanical behavior of a graphite/epoxy fiber composite are presented. Three principal strengths (longitudinal, transverse and shear) and four basic moduli (
Lifshitz, J. M.
core +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Subsystem trade-off environmental control and life support for orbiter phase B contractor [PDF]
Environmental control and life support subsystem for space shuttle ...
Augusti, R., Jasin, J.
core +1 more source

