Results 141 to 150 of about 168,045 (292)
Single‐Cell Profiling Reveals Clonally Expanded CX3CR1+ T Cells in Anti‐NMDA Receptor Encephalitis
Advanced Science, EarlyView.CX3CR1+ T cells are associated with peripheral and central immune alterations in anti‐NMDA receptor encephalitis (NMDAR‐E). They show potential responsiveness to GluN1 (NR1) peptides, potential interactions with peripheral B cells, clonal expansion, increased CD137/CD154 expression, and inflammatory cytokine production. Their preferential cerebrospinal
Lin Yan +13 more
wiley +1 more source
Art Gliner Humor Collection: Humor for the Good Life, 1983
, 1983 Art Gliner Humor Collection: Humor for the Good Life ...
core
Advanced Science, EarlyView.Single‐cell profiling and functional perturbation reveal coordinated JAK1‐pSTAT3 downstream programs in optic neuritis, including MCL1‐dependent fitness of pathogenic CD4+ Tem cells and glycolysis‐linked, cholesterol‐sensitive B‐cell responses associated with RORA. Upadacitinib disrupts this reciprocal T‐B‐cell circuit and alleviates neuroinflammation,
Gengchen Jiang +12 more
wiley +1 more source
CRISPR and Gene Augmentation Rescue Trabecular Meshwork Dysfunction in iPSC Models of Lowe Syndrome
Advanced Science, EarlyView.By modeling Lowe syndrome using patient‐derived iPSCs, this study establishes a human disease model that faithfully recapitulates OCRL deficiency‐associated ciliary and cytoskeletal defects. The model enables evaluation of both mutation‐agnostic DNA augmentation and CRISPR‐mediated mutation correction strategies, both of which restore OCRL function and
Siyu Chen +11 more
wiley +1 more source
The Role of Coping Humour in the Physical and Mental Health of Older Adults [PDF]
Objectives - This study examined the associations among coping humor, other personal/social factors, and the health status of community-dwelling older adults. Method - Survey questionnaires were completed with 73 community dwelling older adults. Included
Elsa Marziali +2 more
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The role of economic conditions on humor generation and attitude towards humorous TV commercials
, 2016 A two-phase experimental study investigates the role of economic conditions on humor generation and on the relationship between perceived humor and attitude toward the ad (Aad).
Christina Boutsouki +5 more
core +1 more source
Traceability of Agri‐Food Products: The Key to Conscious Trade
Agribusiness, EarlyView.ABSTRACT Globalization and growing concerns about sustainability have led to improvements in product traceability, quality, and sustainability. Traceability contributes to environmental protection and supports sustainable development by fostering transparency in agricultural practices and encouraging the responsible use of resources.
Scarlett Queen Almeida Bispo +5 more
wiley +1 more source
, 2017 In a hanbook covering all aspects of language and humor, this contribution focuses on humor and translation. Following a historical overview of the subject, the chapter examines core issues and topics providing sample analyses and ending with new debates.
openaire +2 more sources
A humor szerepe a párkapcsolatokban
A dolgozat áttekinti a humor fogalmát, elméleteit és típusait. A humor pszichológiai és mentálhigiénés funkcióinak (énvédő mechanizmus, érett megküzdési mechanizmus, coping stratégia) bemutatása a párkapcsolatok fejlődési szakaszainak mentén valósult meg.
Szikszai, Henriett
core
Annals of Gastroenterological Surgery, EarlyView.Postoperative infectious complications (PICs) have been associated with poor long‐term outcomes after colorectal cancer surgery, but evidence in the modern minimally invasive era remains limited. In this multicenter cohort of 5377 patients undergoing curative resection, PICs were independently associated with worse overall survival and relapse‐free ...
Takehito Yamamoto +7 more
wiley +1 more source