Results 91 to 100 of about 26,537 (258)

Tuning Mechanoreceptor Signaling Enhances the Adjuvant Effect of Biomaterial Vaccines

open access: yesAdvanced Functional Materials, EarlyView.
Matrix stiffness serves as an independent immunological signal in biomaterial vaccines. Stiffer microporous hydrogel vaccines enhance dendritic cell maturation and migration to draining lymph nodes, promote T follicular helper cell expansion through Yap/Taz signaling, and increase antigen‐specific antibody production.
Lily Shang   +13 more
wiley   +1 more source

Emotion in Humour, Humour in Emotion

open access: yes, 2015
This paper will touch on how and why we communicate humour while concentrating on the emotions provoked and expressed by its use. A look back through the history of humour studies allow us to realise that until recently this field had been somewhat neglected and if taken into consideration at all, seen as negative and non-important in the scheme of ...
openaire   +1 more source

Make‐Use‐Remake: Toward Indefinite Low‐Temperature Material Loops

open access: yesAdvanced Functional Materials, EarlyView.
We introduce a regenerable materials platform built from microparticles bound by a temperature‐responsive polymer shell, enabling strong, processable structures from diverse feedstocks. The material is shaped at low temperatures (80°C) using common manufacturing methods and reprocessed repeatedly in the presence of water, demonstrating stable ...
Nikola Křivánková   +2 more
wiley   +1 more source

Modular Control of PEG‐Poly(2‐Oxazoline) Co‐Assembly Enables Tunable Aggregate Properties for Intraocular Pressure Management

open access: yesAdvanced Healthcare Materials, EarlyView.
A thermo‐responsive poly(2‐oxazoline)‐based injectable formulation is developed to modulate intraocular pressure (IOP) in both normal and hypotonic eyes. By adjusting the PEG content, the aggregation behavior is finely tuned, enabling IOP elevation without long‐term deposition.
Yuji Tanaka   +2 more
wiley   +1 more source

Humour Runs through the Multicoloured Mosaic of Neuropsychotherapy: Scoping Review

open access: yesNeurologijos seminarai
Background. The investigation is devoted to explore the possibilities of humour to treat neuropsychiatric disorders which, in the last decade, have significantly increased. The aim of the study is to describe the growing investigations, in which various
M. Šeduikienė, V. Matonis
doaj   +1 more source

Reprogramming the Immunosuppressive Microenvironment in Triple‐Negative Breast Cancer via FAP‐Targeted Nanoprobes for Multimodal Imaging and Photothermal Therapy

open access: yesAdvanced Materials, EarlyView.
Targeting cancer‐associated fibroblasts (CAFs) with fibroblast activation protein (FAP)‐directed nanoprobes for multimodal imaging and photothermal remodeling of the immunosuppressive microenvironment to enhance immunotherapy in triple‐negative breast cancer (TNBC).
Ling Zhan   +6 more
wiley   +1 more source

High‐Performance Bio‐Glue From the Berries of a Parasitic Plant

open access: yesAdvanced Materials, EarlyView.
We report a fully bio‐based adhesive derived primarily from a (poly)saccharide extract obtained from the berries of the hemi‐parasitic plant mistletoe (Viscum album), supplemented with tannic and malic acid without any further chemical functionalization.
Ufuk Gürer   +8 more
wiley   +1 more source

From Payload‐First Toward Dual‐Mechanism Antibody–Drug Conjugates

open access: yesAdvanced Materials, EarlyView.
Conjugation converts potent antibodies into underexposed carriers. This perspective defines the antibody exposure deficit and maps a mechanism‐first design space from payload‐first to antibody‐first ADC architectures, integrating DAR, linker chemistry, and Fc engineering to guide rational design of constructs that balance targeted cytotoxicity with ...
Xavier Pivot   +3 more
wiley   +1 more source

Low Resistance Interphase Formation at the PEO‐LiTFSI|LGPS Interface in Lithium Solid‐State Batteries

open access: yesAdvanced Materials Interfaces, EarlyView.
Interfacial charge transfer and low‐resistance interphase formation between PEO‐based polymer and Li10GeP2S12 solid electrolytes are investigated using multi‐electrode impedance spectroscopy and advanced analytical techniques such as XPS and ToF‐SIMS.
Ujjawal Sigar   +6 more
wiley   +1 more source

“I did not actually hear George Washington say that”

open access: yesThe European Journal of Humour Research
The topic of US presidential humour has been investigated in the past, specifically as it was used in presidential debates, press conferences, and at the White House Correspondents’ Dinner.
Moshe Machlev
doaj   +1 more source

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