Results 41 to 50 of about 170,404 (235)

BGN/MDK Axis in the Melanoma Tumor Microenvironment Strengthens Tumor Malignancy by Modulating Cancer Cells and Cancer‐Associated Fibroblasts Crosstalk

Advanced Science, EarlyView.
This study reveals that m6A regulators cooperatively upregulate BGN in melanoma, promoting malignancy. Within the tumor microenvironment, CAFs show highest BGN expression. The BGN/MDK axis mediates cancer‐stroma crosstalk, driving normal fibroblast (NF) activation and enhancing the pro‐tumor effect of CAFs, highlighting a promising therapeutic target ...
Hao‐ze Shi, Ming‐yang Wu, Jin‐quan Liu, Cuicui Tian, Li Ma, Xue‐mei Zhou, Ze‐Hao Sun, Zhi‐yong Xu, Run‐dong Zhang, Shan‐yuan Ye, Li‐ming Huang, Yan Wang, Jing‐shu Xiong, Wen‐bo Bu, Xian‐feng Cheng, Jian‐fang Sun, Hao Chen   +16 more
wiley   +1 more source

Systematic Benchmarking of a Noise‐Tolerant Conductive Hydrogel Electrode for Epidermal Bioelectronics

Advanced Science, EarlyView.
General schematic of the approach. Abstract Conventional Silver/Silver Chloride (Ag/AgCl) electrodes remain the clinical standard for electrophysiological monitoring but are hindered by poor skin conformity, mechanical rigidity, and signal degradation, particularly under motion or sweat.
Nazmi Alsaafeen, Ioannis Ziogas, Shirina Alsaedi, Mouza Alshehhi, Shahd Almheiri, Adil Rehman, Khulood Al Shehhi, Hani Saleh, Ahsan Khandoker, Charalampos Pitsalidis, Antoun Khawaja, Anna‐Maria Pappa   +11 more
wiley   +1 more source

Hijacking Democracy: Proposals on the Future of the European Union in Czechia, Hungary, and Slovakia (2015–2022)

Politics and Governance
EU integration has opened new controversies in making sense of democracy. This article studies how discourses on democracy in EU integration open spaces to hijack the concept of democracy, using a novel empirical dataset on proposals for reforming EU ...
Max Steuer
doaj   +1 more source

Hungarian Turanism. From the Birth of the Ideology to Modernity – an Outline of the Problem

Historia i Polityka, 2017
This article is an outline of Hungarian Turanism, Central European ideological phenomenon. The ideology was relatively important in Hungary during the first half of the 20th century and is currently undergoing a revival in the country. Turanism is a very
Michał Kowalczyk
doaj   +1 more source

MVP Inhibits Influenza A Virus‐Induced Ferroptosis by Targeting IRF1 and Increasing FSP1 Activity

Advanced Science, EarlyView.
During IAV infection, MVP inhibits IRF1 polyubiquitination, thereby relieving IRF1‐mediated transcriptional inhibition of FSP1. Consequently, this leads to an upregulation of FSP1 expression, thereby reinforcing the inhibition of ferroptosis. In addition, the MVP can promote myristoylation and ubiquitination of FSP1, enabling its membrane localization ...
Yingbo Chen, Paili Lin, Yongfang Xia, Zhiqiang Liu, Zilu Cheng, Qingmei Zhu, Shiqi Wan, Xiaoyu Chen, Haiyan Bao, Renbo Qiao, Gechang Zhong, Ying Zhu, Shi Liu   +12 more
wiley   +1 more source

‘Hungarian Factor’ in Central and Eastern European Politics of France (Spring — Summer 1920)

Научный диалог
This article examines the role and significance of the “Hungarian factor” in the central and eastern European political landscape of France during the period from April to August 1920.
I. E. Magadeev
doaj   +1 more source

Bifunctional Artificial Enzymes‐Loaded Microgels With LOX‐ and CAT‐Like Activities for Metabolic Reprogramming and Scarless Wound Repair

Advanced Science, EarlyView.
A bifunctional lactate oxidase‐like and catalase‐like artificial enzyme (Metazyme) is integrated into a rod‐shaped microgel (MetaRgel) to enable cascade lactate oxidation and oxygen regeneration. By reprogramming the wound metabolic microenvironment, MetaRgel alleviates excessive lactate accumulation, oxidative stress, hypoxia, and inflammation ...
Yongyuan Kang, Pai Peng, Liang Song, Qiaoxuan Wang, Zilong Zhong, Dongchao Qiu, Yunfan Liu, Kefei Zhao, Xiaofei Dong, Changyou Gao   +9 more
wiley   +1 more source

Adult Sex Ratio as a Demographic Feedback Linking Mating Systems, Parental Care, and Evolution

Advanced Science, EarlyView.
Breeding systems are some of the most diverse social behavior, and our team is investigation the evolutionary causes of this diversity. This review summarises our research carried out at the University of Bath. We argue that demographic components of wild populations, especially the adult sex ratio, plays a key role driving breeding system variation ...
Tamás Székely, Oscar G. Miranda
wiley   +1 more source

Mass appearance of the Ponto-Caspian invader Pontogammarus robustoides in the River Tisza catchment: bypass in the southern invasion corridor?

Knowledge and Management of Aquatic Ecosystems, 2020
The river Danube is the backbone of the ‘southern invasion corridor’, one of the most important passages for the spread of Ponto-Caspian invaders in Europe.
Csabai Zoltán, Borza Péter, Rewicz Tomasz, Pernecker Bálint, Berta Balázs J., Móra Arnold   +5 more
doaj   +1 more source

From Respect to Nazi Allusions: The Changing Emotional Climates of Fidesz Towards Germany after 1990

Politics in Central Europe, 2023
This paper aims to enhance our understanding of the foreign policy of Hungary by looking at the emotional underpinnings of the relationship between Fidesz and Germany.
Hettyey András
doaj   +1 more source