Results 11 to 20 of about 197 (79)
Discovery and Biosynthesis of Celluxanthenes, Antibacterial Arylpolyene Alkaloids From Diverse Cellulose-Degrading Anaerobic Bacteria. [PDF]
Angew Chem Int Ed EnglThe structure and biosynthetic origin of the enigmatic “yellow affinity substance” (YAS) from the anaerobe thermophile Clostridium thermocellum (now: Acetivibrio thermocellus) were elucidated. YAS is a complex of unusual antibacterial arylpolyene alkaloids (celluxanthenes) that are produced by various cellulolytic anaerobes.
Ishida K +9 more
europepmc +2 more sources
Enzyme‐Primed Native Chemical Ligation Produces Autoinducing Cyclopeptides in Clostridia
Angewandte Chemie, Volume 133, Issue 19, Page 10765-10774, May 3, 2021., 2021 The genome‐guided discovery of an autoinducing peptide (AIP) that controls endospore formation in Ruminiclostridium cellulolyticum is reported. A combination of chemical synthesis and chemical complementation assays with a mutant strain reveals that the genuine chemical mediator is a homodetic cyclopeptide (cAIP).
Evelyn M. Molloy +10 more
wiley +2 more sources
From Rags to Riches: Exploiting the Calvin‐Benson‐Bassham Cycle for Biomanufacturing
ChemCatChem, Volume 15, Issue 23, December 7, 2023., 2023 The Calvin‐Benson‐Bassham cycle (CBBc) is widely distributed in nature, but its potential for biomanufacturing is still underexplored. The review highlights opportunities and challenges of exploiting the CBBc for upcycling CO2 to value‐added products using natural or synthetic chemoautotrophic microbial cell factories as catalysts.
Filippo Federici +2 more
wiley +1 more source
Environmental Microbiology, Volume 23, Issue 8, Page 4661-4672, August 2021., 2021 Summary Lactate is a universal metabolite and energy source, yet the mode of lactate metabolism in many strictly anaerobic microorganisms is still enigmatic. This sparked us to investigate the biochemistry and bioenergetics of lactate metabolism in the model acetogenic bacterium Moorella thermoacetica.
Florian P. Rosenbaum +6 more
wiley +1 more source
The FEBS Journal, Volume 288, Issue 6, Page 1839-1858, March 2021., 2021 Several gut bacteria do not convert pentoses via the well‐known pentose phosphate pathway because one of the key enzymes—the transaldolase—is absent. We demonstrated that the transaldolase reaction in Prevotella copri is replaced by the combined reaction of the pyrophosphate‐dependent phosphofructokinase and the fructose‐bisphosphate aldolase.
Laura S. Garschagen +2 more
wiley +1 more source
Food Science &Nutrition, Volume 8, Issue 12, Page 6513-6527, December 2020., 2020 The high‐DHA tuna oil (TO) did produce different influence on the mice fed with high‐fat diet. The benefits of TOs were derived from their modification of the gut microbiota composition and structure in mice. Abstract Studies have documented the benefits of fish oil in different diseases because of its high n‐3 polyunsaturated fatty acid content ...
Jing Zhang +7 more
wiley +1 more source
MicrobiologyOpen, Volume 9, Issue 8, August 2020., 2020 We report the identification and functional characterization of a novel NAD(P)+‐dependent meso‐DAPDH from Numidum massiliense (NmDAPDH). The known meso‐DAPDHs use only NADP+ as a coenzyme, but NmDAPDH was able to use both NADP+ and NAD+ as coenzymes.
Hironaga Akita +3 more
wiley +1 more source
The exceptional form and function of the giant bacterium Ca. Epulopiscium viviparus revolves around its sodium motive force. [PDF]
Proc Natl Acad Sci U S A, 2023 Sannino DR +6 more
europepmc +1 more source
The structure of the Clostridium thermocellum RsgI9 ectodomain provides insight into the mechanism of biomass sensing. [PDF]
Proteins, 2022 Mahoney BJ +4 more
europepmc +1 more source
A dual cohesin-dockerin complex binding mode in Bacteroides cellulosolvens contributes to the size and complexity of its cellulosome. [PDF]
J Biol Chem, 2021 Duarte M +9 more
europepmc +1 more source