Results 41 to 50 of about 2,367 (270)

Sustained Delivery of a Shingles Subunit Vaccine Overcomes Age‐Related Declines in Humoral and Cellular Immunity Relative to Shingrix

open access: yesAdvanced Science, EarlyView.
Sustained delivery of a shingles subunit vaccine from an injectable polymer–nanoparticle hydrogel enhanced the potency, durability, and breadth of immune responses in aged mice while minimizing inflammatory cytokine production and reactogenicity. This strategy decouples immunogenicity from reactogenicity and offers a promising approach to improve ...
Ye Eun Song   +5 more
wiley   +1 more source

TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss

open access: yesAdvanced Science, EarlyView.
TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale   +23 more
wiley   +1 more source

Jerome’s Reception in an Early Eighteenth-Century Hungarian Historical Work

open access: yesClotho, 2021
Works concerning the history of the Hungarian Reform had been almost absent until the second half of the seventeenth century. The relatively peaceful process of the Hungarian Reform, the lack of armed conflicts, and the tragic memory of the battle of ...
Levente Pap
doaj   +1 more source

Mutant KRAS‐m6A Epitranscriptome Axis Promotes Colorectal Cancer and is a Therapeutic Target

open access: yesAdvanced Science, EarlyView.
Mutant KRAS‐m6A axis promotes colorectal cancer (CRC) progression. Mutant KRAS stabilizes METTL3, leading to increased m6A‐modified BCL9L mRNA and translation of BCL9L protein. BCL9L in turn mediates TGF‐β secretion to induce differentiation of Treg and an immunosuppressive microenvironment.
Danyu Chen   +12 more
wiley   +1 more source

Smart Bioinks for 4D Bioprinting: Requirements, Design, and Applications

open access: yesAdvanced Science, EarlyView.
Smart bioinks empower 4D‐bioprinted constructs to dynamically adapt and remodel in response to stimuli, effectively biomimicking native tissues. Artificial Intelligence (AI) and Machine Learning (ML) play a guiding role in their rational design by optimizing relevant properties.
Shangsi Chen   +11 more
wiley   +1 more source

Following the Research. Part II

open access: yesНижневолжский археологический вестник
This article is the second part of a critical review of the works from no. 2 (volume 18) of the Lower Volga Archaeological Bulletin, published in 2019 and dedicated to the anniversary of Prof. I.P. Zasetskaya.
Irina P. Zasetskay
doaj   +1 more source

All’ombra dell’Impero: sui presunti accordi tra Genserico e Attila

open access: yesNuova Antologia Militare, 2023
Through a rereading of historical sources and an analysis of modern historiography, this contribution reconstructs the hypothesis of some alleged contacts between Attila and Genseric, who would have lent mutual help to move their attacks on the Roman ...
Fabiana Rosaci
doaj   +1 more source

Animal‐Based Brands Taking the Plant‐Based Opportunity: A Tasting Experiment Exploring Consumer Acceptance of Plant‐Based Brand Extensions

open access: yesAgribusiness, EarlyView.
ABSTRACT This study investigates how consumer taste and brand equity perceptions shape the acceptance of plant‐based milk products. Using a blind/informed tasting experiment, we evaluated consumers' willingness to buy (WTB) and taste perception of a plant‐based milk alternative produced by a traditional dairy brand, compared with competing plant‐based ...
Federico Parmiggiani   +6 more
wiley   +1 more source

« Attila », « Hongrois », « Huns », « Saints »

open access: yes, 2016
International audience4 notices : « Attila » ; « Hongrois », « Huns » et « Saints »
Bozoky, Edina
core   +1 more source

Attila's Invasion of Gaul in 451 and Re-horsing the Huns

open access: yes, 2021
A debate has emerged on whether the fifth-century Huns evolved into foot soldiers or remained the same horse archers of the steppes as they had been in the fourth century. So far, the debate has focused on ecological and literary evidence.
Linn, Jason, Jason Linn
core   +1 more source

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